Structure-function analysis of the ROR2 cysteine-rich domain reveals a new mechanism of WNT5A reception at the cell surface and provides new insights into the pathogenic mechanisms of Robinow syndrome-driving ROR2 mutations.
Longitudinal and computational analyses reveal an early and temporally stable hippocampal and striatal involvement in reinforcement learning in 6-to-7-year-old children.
The role of lysosomal Ca2+ flux associated with K+ efflux, a well-known event in inflammasome activation in metabolic inflammation and inflammasome activation, has been presented.
Children with ADHD exhibit atypical biological motion perception, with local processing related to social interaction skills and global processing showing age-related improvement.
Amin MD Shakhawat, Jacqueline G Foltz ... Jennifer L Raymond
The capacity for new cerebellum-dependent learning is influenced by the recent history of neural activity in a mouse model of Fragile X syndrome, suggesting a role for metaplasticity.
Actin-independent water influx complements actin-driven cytoskeletal forces to potentiate chemoattractant-induced migration in primary human neutrophils.
Nicolas Loyer, Elizabeth KJ Hogg ... Jens Januschke
PAR-3/Baz function is regulated by CDK1 in asymmetrically dividing cells in the central and peripheral nervous system of Drosophila revealing direct regulation of cell polarity by the cell cycle machinery in the context of cell fate specification.
Bulk and single-cell RNA-seq data demonstrated that muscle stem cells express low levels of canonical endothelial cell markers, including VEGFA receptors, and VEGFA-FLT1 pathway has a drastic effect on muscle stem cell survival through AKT1 in vitro and in vivo.
