Browse our latest research

Page 32 of 1,814
    1. Cell Biology

    Hepatic Transthyretin knockdown alleviates NAFLD by enhancing SERCA2 function and inhibiting endoplasmic reticulum stress

    Yingzi He, Tian Yang ... Fenping Zheng
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Neuroscience

    Detecting Regime Shifts: Neurocomputational Substrates for Over- and Underreactions to Change

    Mu-Chen Wang, George Wu, Shih-Wei Wu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Microsaccades track shifting but not necessarily maintaining covert visual-spatial attention

    Anna M van Harmelen, Freek van Ede
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Cholinergic blockade reveals a role for human hippocampal theta in memory encoding but not retrieval

    Tamara Gedankien, Jennifer Kriegel ... Joshua Jacobs
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience
    2. Physics of Living Systems

    Sub-surface deformation of individual fingerprint ridges during tactile interactions

    Giulia Corniani, Zing S Lee ... Hannes P Saal
    Sub-surface imaging demonstrates that vertical shear beneath fingertip ridges enables high mechanical spatial resolution to support tactile sensing.
    1. Evolutionary Biology

    Coenzyme-protein interactions since early life

    Alma Carolina Sanchez Rocha, Mikhail Makarov ... Klára Hlouchová
    Amino acids that were abundant since the prebiotic era are enriched in protein binding sites of the most ancient coenzymes, supporting the plausibility of an early coenzyme–peptide world.
    1. Structural Biology and Molecular Biophysics

    Crossover in aromatic amino acid interaction strength between tyrosine and phenylalanine in biomolecular condensates

    David De Sancho, Xabier Lopez
    Hydration modulates aromatic interactions, explaining why Tyr is a stronger sticker than Phe in aqueous environments like protein condensates but not in the cores of folded proteins.
    1. Neuroscience

    Biophysical network modeling of temporal and stereotyped sequence propagation of neural activity in the premotor nucleus HVC

    Zeina Bou Diab, Marc Chammas, Arij Daou
    Songbird HVC sequences arise from a balance of ionic currents and structured inhibition, providing a mechanistic framework for understanding cortical sequence generation.
    1. Developmental Biology
    2. Neuroscience

    Ptbp1 is not required for retinal neurogenesis and cell fate specification

    Haley Appel, Rogger P Carmen-Orozco ... Seth Blackshaw
    Loss of function of Ptbp1 in retinal progenitors leads to changes in RNA splicing but does not affect neurogenesis and cell fate specification.