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Page 63 of 1,810
    1. Developmental Biology
    2. Neuroscience

    Premature vision drives aberrant development of response properties in primary visual cortex

    Sophie V Griswold, Stephen D Van Hooser
    Introducing premature visual experience by opening the closed eyelids early in ferrets caused many cells in the primary visual cortex to mature improperly.
    1. Neuroscience

    Bayesian meta-analysis reveals the mechanistic role of slow oscillation-spindle coupling in sleep-dependent memory consolidation

    Thea Ng, Eunsol Noh, Rebecca MC Spencer
    Strong and temporally precise coupling between frontal slow oscillations and fast spindles consistently predicts memory retention across conditions, supporting its role as a fundamental mechanism in sleep-dependent memory consolidation.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    High-content high-resolution microscopy and deep learning-assisted analysis reveals host and bacterial heterogeneity during Shigella infection

    Ana Teresa López-Jiménez, Dominik Brokatzky ... Serge Mostowy
    High-content high-resolution microscopy coupled with deep learning-based analysis reveals novel phenotypes at the single-cell level during Shigella infection.
    1. Cell Biology
    2. Medicine

    Uncovering Shared and Tissue-Specific Molecular Adaptations to Intermittent Fasting in Liver, Brain, and Muscle

    Yibo Fan, Senuri De Silva ... Thiruma V Arumugam
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    Stall force measurement of the kinesin-3 motor KIF1A using a programmable DNA origami nanospring

    Nobumichi Takamatsu, Hiroko Furumoto ... Kumiko Hayashi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Plant Biology

    Structure-guided secretome analysis of gall-forming microbes offers insights into effector diversity and evolution

    Soham Mukhopadhyay, Muhammad Asim Javed ... Edel Perez-Lopez
    Comparative structural genomics identifies unique effector architectures and ankyrin-mediated host targeting, revealing central and conserved strategies that underpin the pathogenicity of diverse gall-forming microbial species across evolutionary lineages.
    1. Physics of Living Systems

    Balancing stability and flexibility when reshaping archaeal membranes

    Miguel Amaral, Felix Frey ... Anđela Šarić
    Archaeal cells mix single-headed and double-headed lipids to construct resilient but flexible membranes to help them survive in extreme environments.
    1. Neuroscience

    Distributed subthreshold representation of sharp wave-ripples by hilar mossy cells

    Ayako Ouchi, Taro Toyoizumi ... Yuji Ikegaya
    Machine learning with whole-cell patch-clamp and local field potential recordings reveals that synaptic responses from five mossy cells, despite their limited population, can significantly reconstruct about 30% of the total hippocampal sharp wave-ripples, highlighting efficient distributed coding within subthreshold activities.
    1. Neuroscience

    Social experience shapes fighting strategies in Drosophila

    Can Gao, Mingze Ma ... Yufeng Pan
    Social enrichment increases the less-frequent high-intensity aggressive tussling and decreases the low-intensity aggressive lunging via distinct sensory and central neurons.
    1. Structural Biology and Molecular Biophysics

    DIRseq as a method for predicting drug-interacting residues of intrinsically disordered proteins from sequences

    Matt MacAinsh, Sanbo Qin, Huan-Xiang Zhou
    A sequence-based method, DIRseq, has been developed to predict drug-interacting residues of intrinsically disordered proteins.