Single-molecule localization imaging shows that the Nipah virus fusion protein forms nanoscale clusters on cell and viral membranes that favor membrane fusion activation.
Angela L Rachubinski, Elizabeth Wallace ... Joaquín M Espinosa
Treatment with a JAK inhibitor normalizes multiple biomarkers of autoinflammation and provides therapeutic benefit for diverse immune skin conditions in individuals with Down syndrome.
Laura-Marie Silbermann, Benjamin Vermeer ... Katarzyna Tych
An exploration of the unanswered questions in how the molecular chaperone Hsp90 supports protein homeostasis, and how single-molecule techniques could drive future breakthroughs in answering them.
Miki Kume, Hanako Koguchi-Yoshioka ... Rei Watanabe
Downregulation of Sema4A in keratinocytes induces psoriatic non-lesional features, with its signaling cascades potentially triggering psoriasis and serving as targets for treatment and prevention.
