Browse our latest research

Page 62 of 1,840
    1. Genetics and Genomics

    A retrospective analysis of 400 publications reveals patterns of irreproducibility across an entire life sciences research field

    Joseph Lemaitre, Désirée Popelka ... Bruno Lemaitre
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics

    Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching

    Kexin Zhang, Timothy Grant, Nikolaus Grigorieff
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Genetics and Genomics

    Reproducibility of Scientific Claims in Drosophila Immunity: A Retrospective Analysis of 400 Publications

    Hannah Westlake, Fabrice David ... Bruno Lemaitre
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    A high-resolution analysis of arrestin2 interactions responsible for CCR5 endocytosis

    Ivana Petrovic, Samit Desai ... Stephan Grzesiek
    Formation and stability of endocytic receptor-arrestin complexes during clathrin-mediated endocytosis are governed by phosphorylation-dependent arrestin-AP2 interactions.
    1. Computational and Systems Biology
    2. Neuroscience

    Predicting human decision-making across task conditions via individuality transfer

    Hiroshi Higashi
    Encoding individual behavioral traits into a low-dimensional latent representation enables the accurate prediction of decision-making patterns across distinct task conditions.
    1. Cancer Biology
    2. Cell Biology

    GMCL1 controls 53BP1 stability and modulates taxane sensitivity

    Yuki Kito, Tania J González-Robles ... Michele Pagano
    GMCL1-dependent degradation of 53BP1 suppresses mitotic surveillance, tuning p53 activation thresholds that govern cell fate decisions and cellular responses after mitosis.
    1. Neuroscience

    Distinct goal location beta frequency dynamics in hippocampus and prefrontal cortex across learning

    Glingna Wang, Nan Zhou ... Jai Y Yu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Dual-feature selectivity enables bidirectional coding in visual cortical neurons

    Katrin Franke, Nikos Karantzas ... Andreas Tolias
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Computational and Systems Biology
    2. Neuroscience

    Biologically informed cortical models predict optogenetic perturbations

    Christos Sourmpis, Carl CH Petersen ... Guillaume Bellec
    Multi area RNN models fitted to in-vivo cortical activity predict behavioral changes induced by optogenetic perturbations, if biologically informed connectivity constraints on the optogenetically targeted inhibitory neurons are applied.
    1. Developmental Biology

    Glial betaPix is essential for blood vessel development in the zebrafish brain

    Shihching Chiu, Qinchao Zhou ... Jing-Wei Xiong
    The glial-specific role of betaPix during cerebral blood vessel development has been revealed by establishing a new betaPix conditional trap allele in zebrafish.