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Page 62 of 1,833
    1. Developmental Biology
    2. Genetics and Genomics

    Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes

    Stephen A Banse, Christine A Sedore ... Patrick C Phillips
    Computer screening identifies that the widely prescribed vitamin A derivative all-trans retinoic acid increases both longevity and late-life health in a powerful genetic model system.
    1. Computational and Systems Biology
    2. Neuroscience

    Predictive modeling of hematoma expansion from non-contrast computed tomography in spontaneous intracerebral hemorrhage patients

    Natasha Ironside, Kareem El Naamani ... VISTA-ICH
    In spontaneous intracerebral hemorrhage patients, features of hematoma expansion can be visualized and predicted from non-contrast computed tomography using transport-based morphometry.
    1. Evolutionary Biology

    Cryptovaranoides is not a squamate

    Michael W Caldwell, Chase D Brownstein ... Tiago R Simões
    Claims for a Triassic-aged crown lizard merit detailed reanalysis, the results of which find that Cryptovaranoides is not only not a lizard, but is a more distantly related diapsid reptile.
    1. Developmental Biology

    Mac-/Lactosylceramide regulates intestinal homeostasis and secretory cell fate commitment by facilitating Notch signaling

    Kebei Tang, Xuewen Li ... Rongwen Xi
    An evolutionarily conserved glycosphingolipid metabolite ensures precise stem cell fate decisions by modulating Delta-Notch signaling dynamics.
    1. Neuroscience

    Vascular endothelial-specific loss of TGF-beta signaling as a model for choroidal neovascularization and central nervous system vascular inflammation

    Yanshu Wang, Amir Rattner ... Jeremy Nathans
    In mice, loss of TGF-beta signaling specifically in vascular endothelial cells leads to retinal hypovascularization, choroidal neovascularization, a pro-inflammatory state within brain and retinal endothelial cells, and an influx of diverse inflammatory cells into the retina.
    1. Neuroscience

    Synergistic MAPT mutations as a platform to uncover modifiers of tau pathogenesis

    Miles R Bryan, Michael F Almeida ... Todd J Cohen
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Solid
    1. Genetics and Genomics

    Microbiota impact Drosophila ageing via Acetobacter, Tachykinin, and TkR99D

    Diana Marcu, David R Sannino ... Adam J Dobson
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Intersection of transient cell states with stable cell types in hippocampus

    Jack A Olmstead, Lauren E King, Brenda L Bloodgood
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Decoding Spine Nanostructure in Mental Disorders Reveals a Schizophrenia-Linked Role for Ecrg4

    Yutaro Kashiwagi, Qingrui Liu ... Shigeo Okabe
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Developmental oligodendrocytes regulate brain function through the mediation of synchronized spontaneous activity

    Ryo Masumura, Kyosuke Goda ... Naofumi Uesaka
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
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