A conserved glucagon signaling pathway links high-fat diet-induced metabolic imbalance to cardiac arrhythmia through hormone-producing cells and heart-innervating neurons that regulate rhythmicity.
Merry Faye E Graff, Emma EM Heeg ... Sarah J Childs
Loss of foxf2 in zebrafish leads to a reduced pericyte progenitor pool in embryos and progresses to severe cerebrovascular defects over the lifespan, suggesting that cerebral small vessel disease in adults has roots in development.
Concurrent decoding of acoustic detail and linguistic structure enables natural, intelligible speech synthesis from limited human cortical recordings, resolving a fundamental constraint in neural speech reconstruction.