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Page 62 of 1,794
    1. Cell Biology

    C-terminal tagging, transmembrane domain hydrophobicity, and an ER retention motif influence the secretory trafficking of the inner nuclear membrane protein emerin

    Jessica Mella, Regan F Volk ... Abigail Buchwalter
    The inner nuclear membrane protein emerin readily traffics through the secretory pathway via its hydrophobic transmembrane domain when tagged with C-terminal GFP.
    1. Cancer Biology
    2. Genetics and Genomics

    NAB2-STAT6 drives an EGR1-dependent neuroendocrine program in solitary fibrous tumors

    Connor Hill, Alexandra Indeglia ... Alessandro Gardini
    Molecular profiling with omics approaches reveals the resemblance between neuroendocrine malignancies and solitary fibrous tumors, rare soft tissue cancers with no effective treatment options.
    1. Neuroscience

    DeePosit, an AI-based tool for detecting mouse urine and fecal depositions from thermal video clips of behavioral experiments

    David Peles, Shai Netser ... Shlomo Wagner
    Thermal imaging, computer vision tools, and an open-source algorithm incorporating a transformer-based video classifier are combined to automatically detect and classify urine and fecal deposits made by male and female mice and their spatio-temporal dynamics during behavioral tests.
    1. Neuroscience

    Optogenetic silencing of hippocampal inputs to the retrosplenial cortex causes a prolonged disruption of spatial working memory

    Bárbara Pinto-Correia, Patrícia Caldeira-Bernardo, Miguel Remondes
    Light-activating a proton pump (eArchT) to silence hippocampal synaptic terminals in the rodent retrosplenial cortex caused a spatial working memory impairment affecting interleaved trials where no light was delivered.
    1. Neuroscience

    Age-dependent predictors of effective reinforcement motor learning across childhood

    Nayo M Hill, Haley M Tripp ... Amy J Bastian
    Reinforcement motor learning of probabilistic tasks shows a protracted developmental trajectory in childhood due to high motor noise and low exploration, though performance deficits can be ameliorated in younger children by reducing task demands in spatial processing and probabilistic reasoning.
    1. Plant Biology

    Rice stripe virus utilizes an Laodelphax striatellus salivary carbonic anhydrase to facilitate plant infection by direct molecular interaction

    Jing Zhao, Xiangyi Meng ... Lili Zhang
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Cell Biology

    Post-translational modifications of microtubules are crucial for malaria parasite transmission

    Kodzo Atchou, Magali Roques ... Volker Heussler
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation

    Beta-Glucan Modulates Monocyte Plasticity and Differentiation Capacity to Mitigate DSS-Induced Colitis

    Yinyin Lv, Yanyun Fan ... Hongzhi Xu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    • Convincing
    1. Neuroscience

    Neural signatures of motor memories emerge in neural network models

    Joanna C Chang, Claudia Clopath, Juan A Gallego
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics

    Functional characterization of the disease-associated CCL2 rs1024611G-rs13900T haplotype: The role of the RNA-binding protein HuR

    Feroz Akhtar, Joselin Hernandez Ruiz ... Srinivas Mummidi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing