Marie Baldenius, Steffen Kautzmann ... Christian Klämbt
In Drosophila larva, the Uninflatable protein helps to switch from FGF-receptor triggered glial growth to Notch triggered wrapping of peripheral axons.
Inhibiting PRMT1 and PRMT5 renders HR-proficient ovarian and breast cancers highly vulnerable to PARP inhibition by suppressing BRCAness and amplifying DNA-damage-driven innate immune signaling.