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Superoxide dismutases, particularly Sod1, differentially tune redox signaling of germline and cyst stem cells, enabling their self-renewal and differentiation, thereby maintaining Drosophila testicular stem cell homeostasis.

Topographically distributed plCoA populations direct innate olfactory responses by signaling to divergent valence-specific targets, linking upstream olfactory identity to downstream valence behaviors, through a population code.

Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor immunity.

Stress-related corticotropin-releasing factor signaling directly modulates striatal cholinergic circuits, and alcohol exposure disrupts this control, revealing a circuit mechanism linking stress, alcohol use, and impaired behavioral flexibility.

Chloroquine interferes with artemisinin activation, and such interactions should be considered when formulating antimalarial drug combinations.

GTPases could be drivers of liver fibrosis in MASLD and potential future therapeutic targets.