Browse our latest research

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    1. Neuroscience

    Dependence of contextual modulation in macaque V1 on interlaminar signal flow

    Shude Zhu, Yu Jin Oh ... Tirin Moore
    Interactions between neurons across cortical layers reflect the balance of feedforward and feedback inputs.
    1. Developmental Biology

    The livebearers platyfish and swordtails partially regenerate their hearts with persistent scarring

    Vincent Hisler, Lana Rees ... Anna Jaźwińska
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Integrating bulk and single cell RNA-seq refines transcriptomic profiles of individual C. elegans neurons

    Alec Barrett, Erdem Varol ... Marc Hammarlund
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    Fragile nucleosomes are essential for RNA Polymerase II to transcribe in eukaryotes

    Lingbo Li, Samuel Hunter ... Gongyi Zhang
    Not revised
    Reviewed Preprint v1
    • Important
    • Inadequate
    1. Neuroscience

    PKD2L1 channels segregated to the apical compartment are the exclusive dual-mode pH sensor in cerebrospinal fluid-contacting neurons

    Magdalena Vitar, Daniel Prieto ... Federico F Trigo
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics

    A default silencing mechanism restrains stress-induced genes in C. elegans

    Orkan Ilbay, Alejandro Rodriguez Gama ... Andrew Fire
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology

    Single-Cell Characterization of Anterior Segment Development: Cell Types, Pathways, and Signals Driving Formation of the Trabecular Meshwork and Schlemm’s Canal

    Revathi Balasubramanian, Nicholas Tolman ... Simon WM John
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Structural Biology and Molecular Biophysics
    2. Medicine

    Direct MRI of Collagen

    Jason Daniel van Schoor, Markus Weiger ... Klaas Paul Pruessmann
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology

    Efficiency and localisation of AURKA degradation by PROTACs is modulated by deubiquitinases UCHL5 and target-selective OTUD6A

    Annabel Cardno, Karen Roberts, Catherine Lindon
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    A conserved Hsp70 phosphorylation regulates cell cycle progression after DNA damage

    Thomas Moss, Alexandra Wooldredge ... Shaeri Mukherjee
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete