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    1. Developmental Biology
    2. Evolutionary Biology

    HoxB-derived hoxba and hoxbb clusters are essential for the anterior–posterior positioning of zebrafish pectoral fins

    Morimichi Kikuchi, Renka Fujii ... Akinori Kawamura
    HoxB-dependent anterior–posterior patterning and the evolutionary origin of pectoral fins.
    1. Neuroscience

    PTBP1 depletion in mature astrocytes reveals distinct splicing alterations without neuronal features

    Min Zhang, Naoto Kubota ... Sika Zheng
    PTBP1 loss in mature astrocytes causes unique astrocytic splicing changes, not neuronal-like, contrasting its role in other non-neuronal cells and indicating PTBP1 depletion alone is ineffective to drive adult-astrocyte-to-neuron conversion.
    1. Neuroscience

    Progressive remote memory decline coincides with parvalbumin interneuron hyperexcitability and enhanced inhibition of cortical engram cells in a mouse model of Alzheimer’s disease

    Julia J van Adrichem, Rolinka J van der Loo ... Ronald E van Kesteren
    Remote memories in Alzheimer’s disease are impaired through loss of inhibitory control over cortical engram neurons by hyperexcitable parvalbumin interneurons.
    1. Cell Biology
    2. Neuroscience

    Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly

    Katherine X Dong, Hui Ji ... Colleen N McLaughlin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Spatially heterogeneous inhibition projects sequential activity onto unique neural subspaces

    Andrew B Lehr, Arvind Kumar, Christian Tetzlaff
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Physics of Living Systems

    Collective epithelial migration mediated by the unbinding of hexatic defects

    Dimitrios Krommydas, Livio Nicola Carenza, Luca Giomi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Synaptic density and relative connectivity conservation maintain circuit stability across development

    Ingo Fritz, Feiyu Wang ... André Ferreira Castro
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    A stochastic RNA editing process targets a select number of sites in individual Drosophila glutamatergic motoneurons

    Andrés B Crane, Michiko O Inouye ... J Troy Littleton
    Patch-seq RNA profiling defines the overall RNA editing landscape and single neuron editing rules for individual genetically defined Drosophila larval motoneurons.
    1. Computational and Systems Biology

    Martinize2 and Vermouth provide a unified framework for molecular topology generation

    Peter C Kroon, Fabian Grünewald ... Siewert J Marrink
    Enabling high-throughput simulations of proteins within the Martini framework.
    1. Neuroscience

    Cholecystokinin modulates age-dependent thalamocortical neuroplasticity

    Xiao Li, Jingyu Feng ... Jufang He
    Cholecystokinin gates age-dependent auditory thalamocortical plasticity and, upon supplementation, reverses age-related plasticity decline and improves frequency discrimination.
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