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The single-cell eQTLGen consortium aims to pinpoint the cellular contexts in which disease-causing genetic variants affect gene expression and its regulation.

Wikidata is continuously-updated resource that could improve the efficiency and accuracy of research in many areas of the life and biomedical sciences.

Establishing a community of 'rigor champions' and building a comprehensive educational platform to teach the principles of rigorous science will help to ensure that the outputs of scientific research remain reliable and robust.

Many of the words used by scientists when reviewing manuscripts, job candidates and grant applications – words such as incremental, novelty, mechanism, descriptive and impact – have lost their meaning.

Improving the research culture of an institution may lead to a fairer, more rewarding and successful environment, but how do you start making changes?

Mentorship, financial security and a positive sense of self-worth increase the likelihood that underrepresented minority and female postdocs will pursue a career in academia.

The rat is much more than a simple model, and a better appreciation of the natural history of wild rats would increase its value as a research organism.

There is a clear need to encourage exploratory research within the framework of open science.

As Eve Marder stands down as a Deputy Editor of eLife, she reflects on the need for journals to change and respond to their environment.

After two heart attacks in three years, an associate professor discusses the challenges of faculty life.