The transcriptional activation of the key developmental timer gene, microRNA lin-4, is driven by the transmembrane transcription factor MYRF following its temporally regulated self-cleavage at the cell membrane.
Bacterial exonuclease III exhibits underestimated enzymatic activities on single-stranded DNA, which may redefine its roles in relevant biological processes and biosensor development.
Anja T Zai, Anna E Stepien ... Richard HR Hahnloser
Zebra finches are capable of overt vocal planning, but to reach a distant vocal target beyond the range of recently produced pitch requires both practice and auditory feedback.
Amanda Chu, Nicholas T Gordon ... Michael A McDannald
Comprehensive behavioral ethograms reveal a fear conditioned cue to elicit a temporally organized suite of behaviors spanning freezing, locomotion, rearing, and jumping.
Macropinocytosis of the signalling receptor LPAR1, by an actin and CYRI-B-dependent mechanism, impacts on progression and spread of pancreatic cancer in a mouse model.
Structure-function analysis of the ROR2 cysteine-rich domain reveals a new mechanism of WNT5A reception at the cell surface and provides new insights into the pathogenic mechanisms of Robinow syndrome-driving ROR2 mutations.
Longitudinal and computational analyses reveal an early and temporally stable hippocampal and striatal involvement in reinforcement learning in 6-to-7-year-old children.
The role of lysosomal Ca2+ flux associated with K+ efflux, a well-known event in inflammasome activation in metabolic inflammation and inflammasome activation, has been presented.
