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Each cone terminal is electrically coupled to around 50 nearby rods, forming a switchable circuit, known as the secondary rod pathway, in which all gap junction channels participate.

Genome editing in a close unicellular relative of animals suggests a premetazoan function of the Hippo pathway effector YAP/TAZ/Yorkie in the regulation of cytoskeletal dynamics and multicellular morphogenesis but not proliferation.

LRRTM1 and LRRTM2 play multifaceted roles in the molecular organization of neuronal circuits through mediating context-dependent functions in synapse development but independent roles in plasticity and cognition.

PBP-lipo is an essential cell-wall synthesis enzyme in Mycobacterium abscessus that localizes to the septum and whose expression is required for normal cell growth and division, as well as mediating sensitivity to several antibiotics including the β-lactams, ampicillin, and amoxicillin.

The frequently observed relationship between perceptual performance and correlated variability in sensory cortex can be explained by observers using a decoding strategy that prioritizes generality for many stimuli over precision.

Interaction strength in Notch signaling determines lateral inhibition patterning and drives fate in the unidimensional cell arrangement of the zebrafish notochord.

Method NEAdriver employs knowledge from global networks to predict novel cancer driver genes in an individualized manner, which is done by accounting for mutations’ co-occurrence in each tumor genome and rigorous statistical evaluation.

Archived histological material from tracing studies, immunohistochemistry, and Golgi impregnations allowed to discover a so far unrecognized structural difference, potentially of functional importance, between neocortical pyramidal neurons of rodent, carnivore, and ungulate as compared to monkey and man.

Social-affective features predict the perceived similarity of real-world actions better than, and independently of, visual and action-related features, and are extracted at the final stage of a temporal gradient in the brain.

Neural recordings from macaque area MT reveal a novel mechanism for detecting moving objects during self-motion, involving neurons with incongruent tuning for depth from motion parallax and binocular disparity cues.