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A genetic tracing study demonstrates that neural progenitor lineage dominance may not be maintained in differentiated progeny, underscoring the critical need for region-specific markers to validate pluripotent stem cell–derived products.

Learning new navigation or memory skills engages flexible brain network dynamics without altering gray matter, white matter, or hippocampal structure.

Blood flow enhances neuronal migration in the adult brain via ghrelin signaling.

Deep3DSIM enables super-resolution imaging >130 µm into complex tissues of fixed and live specimens in an upright configuration, allowing sample manipulation, as well as rapid refocusing without the need to move the specimen or objective lens.

An RNAi based genetic screen and subsequent analyses reveal how dyneins and small GTPases coordinate autophagosome positioning at the ncMTOC in fat cells, advancing understanding of autophagic vesicle transport.

Optical tweezers are used to gain mechanistic insight in the mechanism of inhibition of three distinct compounds being developed as antibiotics against Mycobacterium tuberculosis.

Muscle-derived branched-chain amino acids support thermogenesis in brown adipose tissue, thereby helping maintain body temperature during impaired muscle function or physiological stress.

Cortical feedback to the thalamus lacks the precise spatial organization seen in ascending pathways.

Novel and published data confirm that cartilaginous fishes (chondrichthyans) from many different clades share interesting skeletal features that are similar to bone, but some 'classic' chondrichthyan features are not shared.

Single-cell transcriptome sequencing results of rats intervened with specific mode electroacupuncture (an emerging method for opening the blood-brain barrier).