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Systematic characterization of terminating ribosomes uncovers sequence features influencing ribosome dynamics at stop codons with direct implications in 3' UTR translation.

Genes associated with male reproductive biology appear to be under relaxed selective constraint in a primate species with low sperm competition.

The brain uses separate prediction error and prediction uncertainty signals to trigger event boundaries.

Ligand-driven enhancer activation selectively boosts target gene expression while indirectly repressing neighboring non-target genes, revealing dynamic and competitive regulation during early transcriptional responses.

Gaseous CO₂ acts as a neuron to glia messenger in peripheral myelin to trigger opening of Schwann Cell Cx32 hemichannels in response to axonal action potential propagation.

A robust autofocusing method enables continuous single-cell imaging during rapid cooling, revealing sustained bacterial proliferation hidden by growth arrest inferred from optical-density measurements.

Membrane insertion of Dyngo-4a results in a dynamin-independent inhibition of caveola dynamics, revealing that outer leaflet lipid packing in the plasma membrane contributes to the confinement of caveolae.

Genetic experiments integrated with ChIP-sequencing and CRISPR interference reveal that overexpression of Foxc1 transcriptionally activates the expression of Arhgap36 and dysregulates multiple facets of Hedgehog pathway activity.

A new analysis method to measure the propagation of different membrane currents along complex dendritic trees reveals the conditions leading to burst firing in a computational model of place cells.

Single neurons in mouse sensorimotor cortex are organized by their activity features into distinct subpopulations with area-spanning footprints whose boundaries align closely with anatomical and somatotopic borders.