Browse our Research Articles

Page 7 of 1,449
    1. Physics of Living Systems

    Advantageous and disadvantageous inequality aversion can be taught through learning of others’ preferences

    Shen Zhang, Oriel FeldmanHall ... A Ross Otto
    Like disadvantageous inequity aversion, advantageous inequity aversion can be learned by observing another’s fairness preferences.
    1. Biochemistry and Chemical Biology

    General trends in the calnexin-dependent expression and pharmacological rescue of clinical CFTR variants

    Austin Tedman, John A Olson III ... Jonathan P Schlebach
    Combining deep mutational scanning with CRISPR, interactome measurements, and electrophysiology reveals nuanced effects of the lectin chaperone calnexin on the pharmacological properties of 232 cystic fibrosis variants.
    1. Cell Biology
    2. Developmental Biology

    The oocyte zinc transporter Slc39a10/Zip10 is a regulator of zinc sparks during fertilization in mice

    Atsuko Kageyama, Narumi Ogonuki ... Junya Ito
    The zinc transporter Slc39a10/Zip10 is important for zinc homeostasis during fertilization and embryonic development in mice.
    1. Evolutionary Biology
    2. Neuroscience

    A single-cell transcriptomic atlas reveals resident dendritic-like cells in the zebrafish brain parenchyma

    Mireia Rovira, Giuliano Ferrero ... Valerie Wittamer
    The zebrafish brain combines a conserved heterogeneity of immune cells with a unique dendritic cell-like population.
    1. Evolutionary Biology

    Integration of multi-level dental diversity links macro-evolutionary patterns to ecological strategies across sharks

    Roland Zimm, Vitória Tobias Santos, Nicolas Goudemand
    Shark dentition is a complex and hyper-diverse trait integrating multiple spatial levels, with mid-scale features being most crucial for functional adaptation, revealing evolutionary patterns that offer insights into distinct ecological strategies.
    1. Medicine

    Addressing cultural and knowledge barriers to enable preclinical sex inclusive research

    Brianna N Gaskill, Benjamin Phillips ... Natasha A Karp
    Targeted education corrects key misconceptions and identifies methods to influence intent to use sex-inclusive designs in in vivo studies.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Dock-and-lock binding of SxIP ligands is required for stable and selective EB1 interactions

    Teresa Almeida, Eleanor Hargreaves ... Igor Barsukov
    Structural analysis reveals a two-step EB1-SxIP binding mechanism and identifies ligand mutations that greatly enhance affinity, offering potential therapeutic avenues for targeting microtubule plus end interactions.
    1. Microbiology and Infectious Disease

    The impact of different antimicrobial exposures on the gut microbiome in the ARMORD observational study

    Leon Peto, Nicola Fawcett ... Ann Sarah Walker
    Metagenomic sequencing of stool samples from 225 hospital patients and healthy volunteers reveals the impact of different antimicrobial exposures on the gut microbiome.
    1. Cell Biology

    Evidence of centromeric histone 3 chaperone involved in DNA damage repair pathway in budding yeast

    Prakhar Agarwal, Anushka Alekar ... Santanu K Ghosh
    Genetic and biochemical assays reveal the role of Scm3 in genome stability by regulating the DNA damage checkpoint pathway in budding yeast.