Browse our Research Articles

Independent experimental approaches demonstrate changes in TFAM binding to UVC-irradiated DNA, providing a potential mechanism for DNA damage sensing in the mitochondria.

Uev1A and APC/C degrade CycA to counteract oncogenic Ras, thereby protecting against cell death in polyploid Drosophila nurse cells and suppressing overgrowth in diploid germline and human colorectal tumor cells.

Activity fluctuations, or noise correlations, are robust measures of neuronal connectivity and they reveal that neural circuity controls mixing of information at a granular level across millimeter-length scales.

A novel pipeline for analyzing longitudinal two-photon microscopy data of cerebrovasculature in mice interrogates the vasculature network before and after optogenetic stimulation, revealing new insights into their coordination.

Being responsible for a partner's adverse outcomes is associated with anterior insula activation, while the superior temporal sulcus tracks prediction errors for the partner's reward resulting from the participant's decisions.

The severity of active tuberculosis in a high-burden population is not explained by host or pathogen genetic variation, suggesting a dominant role for social and environmental factors.

In-cell biophysical analyses identify a sequence-encoded energy storage function of innate immune adaptor proteins that allows cells to respond quickly and decisively to pathogenic signals.

An automated bioluminescent image analysis framework, maRQup, parametrizes tumor dynamics and provides quantitative metrics, enabling large-scale evaluation and optimization of preclinical cancer immunotherapies.

NAT10-mediated mRNA acetylation links neural activity to local protein synthesis at synapses, influencing memory consolidation.

Stable pressure gradients can arise in cells from the combination of actomyosin-generated cortical tension, cytoplasmic poroelasticity, and water flows across the membrane.