Browse our Research Articles

Page 8 of 1,343
    1. Microbiology and Infectious Disease

    Capsular polysaccharide restrains type VI secretion in Acinetobacter baumannii

    Nicolas Flaugnatti, Loriane Bader ... Melanie Blokesch
    Capsular polysaccharides of Acinetobacter baumannii regulate type VI secretion system activity, balancing self-protection with interbacterial competitiveness.
    1. Cell Biology

    Hypersensitive intercellular responses of endometrial stromal cells drive invasion in endometriosis

    Chun-Wei Chen, Jeffery B Chavez ... Bruce J Nicholson
    A unique functional comparison of the major endometrial cell types from 44 control and endometriosis patients demonstrates not only a uterine origin of the disease, but also that endometrial to mesothelial cell gap junctions are required for invasive lesion formation.
    1. Neuroscience

    Assessing the balance between excitation and inhibition in chronic pain through the aperiodic component of EEG

    Cristina Gil Avila, Elisabeth S May ... Markus Ploner
    Multiverse analysis of the aperiodic component of the electroencephalography (EEG) power spectrum yielded robust evidence against a relationship to chronic pain, guiding further research on EEG biomarkers of chronic pain.
    1. Computational and Systems Biology

    AI-driven automated discovery tools reveal diverse behavioral competencies of biological networks

    Mayalen Etcheverry, Clément Moulin-Frier ... Michael Levin
    A novel methodology, using diversity search AI algorithms, for exploring the space of possible behaviors of gene regulatory networks, from the perspective of generic problem-solving agents navigating their environment.
    1. Neuroscience

    Geometry and dynamics of representations in a precisely balanced memory network related to olfactory cortex

    Claire Meissner-Bernard, Friedemann Zenke, Rainer W Friedrich
    Computational modeling revealed that balanced assemblies of excitatory and inhibitory neurons shape representational manifolds in olfactory cortex-like recurrent networks, resulting in joint maps of sensory and semantic information.
    1. Evolutionary Biology

    Heterozygote advantage can explain the extraordinary diversity of immune genes

    Mattias Siljestam, Claus Rueffler
    An eco-evolutionary model shows that heterozygote advantage can maintain over 100 major histocompatibility complex alleles, providing a potent explanation for extraordinary immune gene diversity and challenges previous models that predicted limited allele coexistence.
    1. Cancer Biology
    2. Computational and Systems Biology

    Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility

    Rosalyn W Sayaman, Masaru Miyano ... Mark A LaBarge
    Breast luminal epithelial cells are the hotspots of aging-associated changes, which prime aged epithelia for oncogenic gene activation and may explain individual differences in breast cancer susceptibility due to the aging-associated increase in gene expression variances in luminal epithelia.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

    Liza Dahal, Thomas GW Graham ... Xavier Darzacq
    Type II nuclear receptors do not always compete for a limiting pool of their obligate partner RXRa.
    1. Neuroscience

    Mapping patterns of thought onto brain activity during movie-watching

    Raven Star Wallace, Bronte Mckeown ... Jonathan Smallwood
    Decoding brain activity using a novel paradigm unveils distinct neural signatures of subjective experiences during movie-watching.