Browse our Research Articles

Page 8 of 1,399
    1. Neuroscience

    Cognitive control of behavior and hippocampal information processing without medial prefrontal cortex

    Eun Hye Park, Kally C O'Reilly Sparks ... André A Fenton
    Rodent medial prefrontal cortex is not crucial for an active place avoidance task requiring cognitive control evidenced by hippocampal activity that purposefully alternates between task-relevant and task-irrelevant representations of the environment.
    1. Neuroscience
    2. Physics of Living Systems

    The geometry and dimensionality of brain-wide activity

    Zezhen Wang, Weihao Mai ... Quan Wen
    Neural activity patterns in randomly sampled neuron groups statistically match whole-brain dynamics, revealing a scale-invariant organizational principle that enables robust and efficient computation across brain regions and species.
    1. Microbiology and Infectious Disease

    Regulative synthesis of capsular polysaccharides in the pathogenesis of Streptococcus suis

    Xingye Wang, Jie Wang ... Beinan Wang
    Streptococcus suis enhances its pathogenicity by dynamically expressing capsular polysaccharides.
    1. Neuroscience

    Brain-derived exosomal hemoglobin transfer contributes to neuronal mitochondrial homeostasis under hypoxia

    Zhengming Tian, Yuning Li ... Jia Liu
    Exosomal mRNA transfer from non-neuronal cells to neurons under hypoxia drives hemoglobin expression and preserves mitochondrial homeostasis as an intercellular protective mechanism.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Mapping HIV-1 RNA structure, homodimers, long-range interactions and persistent domains by HiCapR

    Yan Zhang, Jingwan Han ... Zhihu Zhao
    HiCapR uncovers HIV RNA homodimers and long-range interactions that show structural dynamics critical for viral packaging and assembly.
    1. Computational and Systems Biology
    2. Neuroscience

    Evidence from pupillometry, fMRI, and RNN modelling shows that gain neuromodulation mediates task-relevant perceptual switches

    Gabriel Wainstein, Christopher J Whyte ... James M Shine
    Phasic neuromodulatory bursts actively drive adaptive perceptual updating by triggering large-scale brain network reconfigurations, as demonstrated through integrated pupillometry, fMRI, and computational modelling.
    1. Microbiology and Infectious Disease

    Salmonella exploits host- and bacterial-derived β-alanine for replication inside host macrophages

    Shuai Ma, Bin Yang ... Lingyan Jiang
    Salmonella orchestrates synergistic exploitation of host- and bacterial-derived β-alanine enhancing ZnuABC-mediated zinc assimilation to drive intracellular replication and systemic infection.
    1. Microbiology and Infectious Disease

    Efficacy and mechanism of action of cipargamin as an antibabesial drug candidate

    Hang Li, Shengwei Ji ... Xuenan Xuan
    The potential of repurposing cipargamin for treating Babesia species offers both theoretical advancements and practical applications in combating parasitic infections.
    1. Developmental Biology
    2. Neuroscience

    In mice, discrete odors can selectively promote the neurogenesis of sensory neuron subtypes that they stimulate

    Kawsar Hossain, Madeline Smith ... Stephen W Santoro
    The neurogenesis rates of some olfactory sensory neuron subtypes are selectively accelerated in mice that are exposed to odors that stimulate those subtypes.
    1. Cancer Biology

    A multi-gene predictive model for the radiation sensitivity of nasopharyngeal carcinoma based on machine learning

    Kailai Li, Junyi Liang ... Hui Meng
    A machine learning-derived multi-gene score effectively predicts radiation sensitivity in nasopharyngeal carcinoma by integrating immune characteristics and radiosensitivity-related pathways.