Browse our Research Articles

NAT10-mediated mRNA acetylation links neural activity to local protein synthesis at synapses, influencing memory consolidation.

Stress-related corticotropin-releasing factor signaling directly modulates striatal cholinergic circuits, and alcohol exposure disrupts this control, revealing a circuit mechanism linking stress, alcohol use, and impaired behavioral flexibility.

Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor immunity.

GTPases could be drivers of liver fibrosis in MASLD and potential future therapeutic targets.

Stable pressure gradients can arise in cells from the combination of actomyosin-generated cortical tension, cytoplasmic poroelasticity, and water flows across the membrane.

Competition between Quaking and SF1 for a subset of ACUAA intron branch sites influences alternative splicing in different tissues and organisms.

Studying the reproductive life history of an acoel reveals that a body-size-dependent program regulates organ growth and regeneration dynamics and discovers a novel form of egg-laying behavior.

Inactivation of beta 1,4-galactosyltransferase 1 leads to enhanced T-cell receptor activation and CD8⁺ T-cell function by affecting the galactosylation of T-cell receptor and CD8.

Unique extracellular vesicle microRNA signatures resulting from G protein-coupled receptor activation indicate distinct downstream signaling and functional networks by receptor, with implications for developing new drugs and understanding their long-term and off-target effects.

Functional connectivity reveals brain attractors that match predictions of free‑energy‑minimizing attractor theory, yielding an interpretable generative model of brain dynamics in rest, task, and disease.