Browse our Research Articles

Page 6 of 1,343
    1. Chromosomes and Gene Expression

    Sir2 and Fun30 regulate ribosomal DNA replication timing via MCM helicase positioning and nucleosome occupancy

    Carmina Lichauco, Eric J Foss ... Antonio Bedalov
    Precocious ribosomal DNA replication in sir2 mutants requires Fun30.
    1. Cancer Biology
    2. Immunology and Inflammation

    Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers

    Sofia V Krasik, Ekaterina A Bryushkova ... Ekaterina O Serebrovskaya
    BCR profiling of tumor infiltrating B cells alongside with circulating and lymph node-resident B cells deepens understanding of their unique properties.
    1. Neuroscience

    A septo-hypothalamic-medullary circuit directs stress-induced analgesia

    Devanshi Piyush Shah, Pallavi Raj Sharma ... Arnab Barik
    Acute stress and anxiety can suppress pain, here we reveal a multi-nodal circuit in the brain that connects the two.
    1. Cell Biology
    2. Computational and Systems Biology

    Unbiased identification of cell identity in dense mixed neural cultures

    Sarah De Beuckeleer, Tim Van De Looverbosch ... Winnok H De Vos
    Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.
    1. Microbiology and Infectious Disease

    Altering the redox status of Chlamydia trachomatis directly impacts its developmental cycle progression

    Vandana Singh, Scot P Ouellette
    Differentiation of the pathogenic bacterium, Chlamydia trachomatis, from its non-infectious to infectious form is linked to the redox state of the organism.
    1. Neuroscience

    Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors

    Vincent Huson, Wade G Regehr
    Different glutamate receptors have specialized roles that allow cerebellar unipolar brush cells to transform realistic mossy fiber input patterns into a continuum of temporal responses.
    1. Medicine

    A new preprocedural predictive risk model for post-endoscopic retrograde cholangiopancreatography pancreatitis: The SuPER model

    Mitsuru Sugimoto, Tadayuki Takagi ... Hiromasa Ohira
    A PEP risk scoring model that could be calculated before ERCP, SuPER model, may aid in preventing PEP by allowing selection of the appropriate expert endoscopist and useful PEP prophylaxes.
    1. Neuroscience

    Prolactin-mediates a lactation-induced suppression of arcuate kisspeptin neuronal activity necessary for lactational infertility in mice

    Eleni Hackwell, Sharon R Ladyman ... David R Grattan
    Lactational infertility in mice is dependent on prolactin action in kisspeptin neurons.
    1. Immunology and Inflammation

    Early and delayed STAT1-dependent responses drive local trained immunity of macrophages in the spleen

    Aryeh Solomon, Noa Bossel Ben-Moshe ... Roi Avraham
    In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.