Browse our Research Articles

Page 78 of 1,455
    1. Immunology and Inflammation

    PIM kinase control of CD8 T cell protein synthesis and cell trafficking

    Julia M Marchingo, Laura Spinelli ... Doreen A Cantrell
    Parallel proteomics and transcriptomics data reveal that PIM kinases have a context-dependent role in promoting mouse CD8 T cell protein translation, effector function, and cell homing.
    1. Medicine

    Transparency of research practices in cardiovascular literature

    Gabriel O Heckerman, Eileen Tzng ... Adrienne Mueller
    Based on a standardized screening process, the simple majority of reviewed cardiovascular research publications lack sufficient information needed for the study to be replicated or reproduced.
    1. Genetics and Genomics
    2. Neuroscience

    Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs

    Jiro Yoshino, Sonali S Mali ... Jay Z Parrish
    Epidermal mechanosensory responses contribute to acute detection of noxious mechanical stimuli and promote a form of prolonged mechanical hypersensitivity.
    1. Neuroscience

    Selective attention and sensitivity to auditory disturbances in a virtually real classroom

    Orel Levy, Shirley Libman Hackmon ... Elana Zion Golumbic
    Neural and gaze-based metrics provide novel insights into individual differences in attention and distractability in a simulated classroom.
    1. Genetics and Genomics
    2. Neuroscience

    Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease

    Zachary Gaertner, Cameron Oram ... Rajeshwar Awatramani
    A high-resolution atlas of the mouse dopaminergic system was obtained using single-nuclei RNA sequencing and spatial transcriptomics revealing molecular changes in a prodromal model of Parkinson's disease.
    1. Neuroscience

    Reproducibility of in vivo electrophysiological measurements in mice

    International Brain Laboratory, Kush Banga ... Yizi Zhang
    An electrophysiology dataset generated by 10 laboratories from mice during perceptual decision-making reveals that reproducibility of systems neuroscience data requires stringent histological and electrophysiological quality-control criteria and careful analytical choices.
    1. Ecology

    Effects of blood meal source and seasonality on reproductive traits of Culex quinquefasciatus (Diptera: Culicidae)

    Kevin Alen Rucci, Gabriel Barco ... Adrián Díaz
    Interaction between blood meal source and seasonality shapes reproductive outputs in Culex quinquefasciatus mosquitoes, providing insight into mechanisms driving seasonal host shift.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Seasonally migratory songbirds have different historic population size characteristics than resident relatives

    Kevin Winker, Kira Delmore
    Paleodemographic analyses in a hypothesis-testing framework show that the major life-history trait of seasonal migration has strong effects on long-term effective population sizes in a clade of songbirds.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Rtf1 HMD domain facilitates global histone H2B monoubiquitination and regulates morphogenesis and virulence in the meningitis-causing pathogen Cryptococcus neoformans

    Yixuan Jiang, Ying Liang ... Youbao Zhao
    Rtf1 HMD is related to H2B ubiquitination and its downstream H3K4 methylation in both C. neoformans and C. deneoformans, thereby affecting its yeast-to-hypha transition and virulence.
    1. Immunology and Inflammation

    Diversity and functional specialization of oyster immune cells uncovered by integrative single-cell level investigations

    Sebastien De La Forest Divonne, Juliette Pouzadoux ... Emmanuel Vignal
    Single-cell and functional analyses uncover distinct immune cell types, revealing specialized functions and deepening insight into invertebrate cellular immunity.