Browse our Research Articles

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    1. Microbiology and Infectious Disease

    Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses

    Cody J Warren, Arturo Barbachano-Guerrero ... Sara L Sawyer
    Resurrection of ancient forms of CD4 reveals how retroviruses have placed selective pressure on this gene in apes, acting to propagate infection-resistant alleles.
    1. Neuroscience

    Trends in self-citation rates in high-impact neurology, neuroscience, and psychiatry journals

    Matthew Rosenblatt, Saloni Mehta ... Dustin Scheinost
    Self-citation rates differed by geographic region, seniority, gender, and field, which may ultimately affect the perceived influence of authors in these subgroups in neuroscience literature.
    1. Immunology and Inflammation

    Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms

    Jie Zhang, Hui Tang ... Yu Zhang
    Dendritic cell (DC)-derived IL-27 establishes CD4+ T cell bias against IFN-γ via STAT1 and epigenetics, linking thymic development to autoimmune mechanisms.
    1. Immunology and Inflammation

    Reprogramming of GM-CSF-dependent alveolar macrophages through GSK3 activity modulation

    Israel Ríos, Cristina Herrero ... Angel L Corbí
    Chemical inhibition or genetic downregulation of glycogen synthase kinase-3 reprograms human monocyte-derived macrophages by enhancing their anti-inflammatory, homeostatic, and reparative functions.
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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    SARS-CoV-2 nsp16 is regulated by host E3 ubiquitin ligases, UBR5 and MARCHF7

    Li Tian, Zongzheng Zhao ... Zhaolong Li
    E3 ligases UBR5 and MARCHF7 restrict SARS-CoV-2 replications through targeting nsp16.
    1. Cancer Biology
    2. Genetics and Genomics

    Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer

    Arkajyoti Bhattacharya, Thijs S Stutvoet ... Rudolf SN Fehrmann
    Independent component analysis of ovarian cancer transcriptomes reveals distinct transcriptional patterns associated with overall survival.
    1. Neuroscience

    Convolutional networks can model the functional modulation of the MEG responses associated with feed-forward processes during visual word recognition

    Marijn van Vliet, Oona Rinkinen ... Riitta Salmelin
    Convolutional neural networks can model the early feed-forward components of the MEG evoked response during visual word recognition.
    1. Ecology

    Maternal behavior influences vocal practice and learning processes in the greater sac-winged bat

    Ahana Aurora Fernandez, Nora Serve ... Mirjam Knörnschild
    Non-tutorial feedback shapes song acquisition in a mammalian vocal learner.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Observation of persister cell histories reveals diverse modes of survival in antibiotic persistence

    Miki Umetani, Miho Fujisawa ... Yuichi Wakamoto
    Time-lapse analyses of millions of antibiotic-stressed Escherichia coli characterize the diverse single-cell dynamics of persister cells that depend on antibiotics, culture conditions, and pre-exposure history.
    1. Neuroscience

    Role of posterior medial thalamus in the modulation of striatal circuitry and choice behavior

    Alex J Yonk, Ivan Linares-García ... David J Margolis
    A thalamic nucleus plays a previously unappreciated role in behavioral arousal and learning through its innervation of the dorsal striatum.