Browse our Tools and Resources

Page 5 of 81
    1. Computational and Systems Biology
    2. Neuroscience

    A reductionist paradigm for high-throughput behavioural fingerprinting in Drosophila melanogaster

    Hannah Jones, Jenny A Willis ... Giorgio F Gilestro
    Coccinella, an open-source framework, combines real-time tracking on microcomputers with statistical learning, optimising behaviour analysis in Drosophila melanogaster while surpassing other advanced systems in throughput and performance.
    1. Developmental Biology

    Single-cell profiling coupled with lineage analysis reveals vagal and sacral neural crest contributions to the developing enteric nervous system

    Jessica Jacobs-Li, Weiyi Tang ... Marianne E Bronner
    Single-cell transcriptome analysis of sacral compared with vagal neural crest-derived cells in the developing chick enteric nervous system reveals both similarities and differences between these two cell populations.
    1. Cell Biology

    Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp

    Abigail C Neininger-Castro, James B Hayes ... Dylan Tyler Burnette
    Software is introduced for the rapid and comprehensive quantification of sarcomere-containing myofibrils and their precursors in cardiac myocytes, aiding in the advancement of cardiovascular cell biology investigations.
    1. Neuroscience

    Bayesian analysis of phase data in EEG and MEG

    Sydney Dimmock, Cian O'Donnell, Conor Houghton
    A Bayesian model of phase angles illustrates a novel approach to the analysis of phase coherence in frequency-tagged experiments.
    1. Neuroscience

    Pynapple, a toolbox for data analysis in neuroscience

    Guillaume Viejo, Daniel Levenstein ... Adrien Peyrache
    Pynapple advances data analysis in systems neuroscience with a versatile, open-source framework that uses common objects to handle diverse data streams, ensuring reliable and reproducible analysis while maintaining long-term backward compatibility.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

    Sevim Kahraman, Kimitaka Shibue ... Rohit N Kulkarni
    Live human pancreatic α-cells can be purified effectively using zinc-based reaction probe diacetylated Zinpyr1 and cultured as pseudoislets without losing their viability and function.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    PerTurboID, a targeted in situ method reveals the impact of kinase deletion on its local protein environment in the cytoadhesion complex of malaria-causing parasites

    Heledd Davies, Hugo Belda ... Moritz Treeck
    A new mass spectrometry-based method to identify and quantify changes in a subcellular local protein environment shows the impact of deletion of a kinase the human malaria parasites export into the host cell.
    1. Computational and Systems Biology

    Bactabolize is a tool for high-throughput generation of bacterial strain-specific metabolic models

    Ben Vezina, Stephen C Watts ... Kelly L Wyres
    Bactabolize is a pipeline for rapid and scalable production of accurate bacterial strain-specific metabolic models and growth phenotype predictions.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Diminishing neuronal acidification by channelrhodopsins with low proton conduction

    Rebecca Frank Hayward, F Phil Brooks III ... Adam E Cohen
    Many channelrhodopsins acidify cells, but two new ones do not.
    1. Neuroscience

    Rodent ultrasonic vocal interaction resolved with millimeter precision using hybrid beamforming

    Max L Sterling, Ruben Teunisse, Bernhard Englitz
    The accuracy of the Hybrid Vocalization Localizer (HyVL) brings a revolution to the study of social vocalizations of rodents and other animals, where vocalizations often occur in close proximity, and will empower downstream analysis of sequence and semantic analyses.