Browse our Tools and Resources

Page 4 of 87
    1. Stem Cells and Regenerative Medicine

    Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation

    Mami Matsuo-Takasaki, Sho Kambayashi ... Yohei Hayashi
    Adding suppressors of spontaneous differentiation enables precise control of human induced pluripotent stem cell (hiPSC) status in suspension culture conditions and leads to scalable and automated cell therapy using hiPSCs.
    1. Cell Biology

    Visualization of endogenous G proteins on endosomes and other organelles

    Wonjo Jang, Kanishka Senarath ... Nevin A Lambert
    Heterotrimeric G proteins are less abundant on endosomes and organelles than on the plasma membrane.
    1. Neuroscience

    Precise control of neural activity using dynamically optimized electrical stimulation

    Nishal Pradeepbhai Shah, AJ Phillips ... EJ Chichilnisky
    A novel method of electrical stimulation to precisely control neural activity for sensory restoration exhibits improvements in visual stimulus reconstruction, enables efficient hardware design, and extends to naturalistic conditions.
    1. Neuroscience

    Predictably manipulating photoreceptor light responses to reveal their role in downstream visual responses

    Qiang Chen, Norianne T Ingram ... Fred Rieke
    Quantitative models for responses of rod and cone photoreceptors are developed that allow direct tests of the impact of the photoreceptors on responses of downstream visual neurons.
    1. Neuroscience

    Development of a Marmoset Apparatus for Automated Pulling to study cooperative behaviors

    Olivia C Meisner, Weikang Shi ... Steve WC Chang
    The Marmoset Apparatus for Automated Pulling provides a powerful and scalable experimental platform for studying behavioral and neural mechanisms underlying cooperation in freely moving marmosets.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    DGRPool, a web tool leveraging harmonized Drosophila Genetic Reference Panel phenotyping data for the study of complex traits

    Vincent Gardeux, Roel PJ Bevers ... Bart Deplancke
    The DGRPool web tool aggregates phenotyping data from the Drosophila Genetic Reference Panel, streamlining genetic association studies and offering new insights into genetic and phenotypic variation in complex traits.
    1. Neuroscience

    A neurotransmitter atlas of C. elegans males and hermaphrodites

    Chen Wang, Berta Vidal ... Oliver Hobert
    Expression pattern analysis of neurotransmitter synthesis, secretion, and reuptake machinery reveals animal-wide usage of neurotransmitters in both sexes of Caenorhabditis elegans.
    1. Neuroscience

    Robust optogenetic inhibition with red-light-sensitive anion-conducting channelrhodopsins

    Johannes Oppermann, Andrey Rozenberg ... Peter Hegemann
    Engineered anion-conducting channelrhodopsins with enhanced red-light sensitivity and accelerated kinetics enable precise, low-intensity optical silencing of neurons, advancing optogenetic control in neuroscience research.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Regulatory genome annotation of 33 insect species

    Hasiba Asma, Ellen Tieke ... Marc S Halfon
    Over 2.8 million tissue-specific gene regulatory sequences are predicted for 33 insect genomes, using a simple computational workflow with only the genome sequence and a basic gene annotation as input.
    1. Evolutionary Biology
    2. Medicine

    The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis

    Rion Brattig-Correia, Joana M Almeida ... Paulo Navarro-Costa
    An interdisciplinary research platform reveals that the transcriptional identity of metazoan male germ cells is built around a small network of deeply conserved gene interactions with an overarching functional impact.