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Page 13 of 1,863
    1. Neuroscience

    Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing

    Katrina Bartas, Pieter Derdeyn ... Kevin T Beier
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys

    Kathryn Branam, Joshua I Gold, Long Ding
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Neuroscience

    Disentangling Cephalopod Chromatophores Motor Units with Computer Vision

    Mathieu DM Renard, Johann Ukrow ... Gilles Laurent
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology

    The Drosophila EGF domain protein uninflatable sets the switch between wrapping glia growth and axon wrapping instructed by Notch

    Marie Baldenius, Steffen Kautzmann ... Christian Klämbt
    In Drosophila larva, the Uninflatable protein helps to switch from FGF-receptor triggered glial growth to Notch triggered wrapping of peripheral axons.
    1. Neuroscience

    Automatic learning mechanisms for flexible human locomotion

    Cris Rossi, Kristan Leech ... Amy J Bastian
    A flexible but automatic stimulus-response mapping mechanism complements forward model recalibration in walking adaptation, immediately accounting for perceived changes in the environment through perception altered by the same recalibration process.
    1. Chromosomes and Gene Expression

    The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements

    Andria Koulle, Oluwaseun Ogundele ... Brian Hendrich
    CHD4 directly limits transcription factor binding to chromatin, which prevents activation of silent or cryptic enhancers but facilitates activity of active enhancers.
    1. Cancer Biology

    Repression of PRMT activities sensitize human homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment

    Youyou Zhang, Mu Xu ... Xiaowen Hu
    Inhibiting PRMT1 and PRMT5 renders HR-proficient ovarian and breast cancers highly vulnerable to PARP inhibition by suppressing BRCAness and amplifying DNA-damage-driven innate immune signaling.
    1. Neuroscience

    Information, certainty, and learning

    Justin A Harris, Charles Randy Gallistel
    The acquisition and expression of Pavlovian conditioned responding are shown to be lawfully related to objectively specifiable temporal properties of the events the animal is learning about.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B

    Ozkan Aydemir, Jeffrey A Bailey ... TEDDY Study Group
    HLA-DRA intronic haplotype associates with opposite effects on type 1 diabetes and celiac disease, refining genetic risk prediction and implicating complement genes C4A and C4B in divergent autoimmune pathways.
    1. Developmental Biology

    Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells

    Hiroki Tsutsumi, Tomoki Chiba ... Hiroshi Asahara
    Single-cell profiling reveals CD55+CD248+ tendon stem/progenitor cells.
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