Browse the latest research

Page 13 of 1,908
    1. Cell Biology
    2. Genetics and Genomics

    Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

    Serhiy Havrylov, Armin M Gamper, Ordan J Lehmann
    Genetic experiments integrated with ChIP-sequencing and CRISPR interference reveal that overexpression of Foxc1 transcriptionally activates the expression of Arhgap36 and dysregulates multiple facets of Hedgehog pathway activity.
    1. Cell Biology
    2. Computational and Systems Biology

    Lipid packing contributes to the confinement of caveolae to the plasma membrane

    Elin Larsson, Aleksei Kabedev ... Richard Lundmark
    Membrane insertion of Dyngo-4a results in a dynamin-independent inhibition of caveola dynamics, revealing that outer leaflet lipid packing in the plasma membrane contributes to the confinement of caveolae.
    1. Cell Biology
    2. Neuroscience

    Activity-dependent CO2 production in the axon triggers opening of Connexin32 in the Schwann cell paranode

    Jack Butler, Lowell Mott ... Nicholas Dale
    Gaseous CO2 acts as a neuron to glia messenger in peripheral myelin to trigger opening of Schwann Cell Cx32 hemichannels in response to axonal action potential propagation.
    1. Computational and Systems Biology
    2. Neuroscience

    SqueakPose Studio, an end-to-end platform for pose estimation and real-time edge-AI deployment

    David L Haggerty, Caleb Browning Darden, David Lovinger
    Integrated pose estimation, video acquisition, and edge deployment tools make real-time behavioral analysis more accessible to neuroscience laboratories.
    1. Neuroscience

    NPAS4 refines spatial and temporal firing in CA1 pyramidal neurons

    Anja Payne, Daniel A Heinz ... Brenda L Bloodgood
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    A simplified and highly efficient cell-free protein synthesis system for prokaryotes

    Xianshengjie Lang, Changbin Zhang ... Wenfei Li
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    A protease-sensing circuit links neutrophil inflammation to virulence regulation in Streptococcus pyogenes

    Stephanie Guerra, Ananya Dash ... Christopher N LaRock
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cell Biology

    CROP2, a Retriever-PROPPIN Complex Mediating Protein Export from Endosomes to the Plasma Membrane

    Maria Giovanna De Leo, Andreas Mayer
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology

    Trpv4 links environmental temperature to testicular differentiation in hermaphroditic ricefield eel

    Yang Zhi, Luo Tingting ... Sun Yuhua
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Early Visual Cortex Supports One-Shot Episodic Memory via Spatially Tuned Reactivation

    Robert Woodry, Jonathan Winawer, Serra E Favila
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid