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    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Genome reorganization and its functional impact during breast cancer progression

    Kathleen S Metz Reed, Andrew Fritz ... Tom Misteli
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Developmental Biology
    2. Immunology and Inflammation

    Mitochondrial metabolic remodeling drives innate immune activation in Drosophila hemocytes

    Daewon Lee, Ferdinand Koranteng ... Jiwon Shim
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Conformational Variability of HIV-1 Env Trimer and Viral Vulnerability

    Yiwei Cao, Wonpil Im
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Simplified model of intrinsically bursting neurons

    Nikhil X Bhattasali, Lerrel Pinto, Grace W Lindsay
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology

    Single-step in vitro ribosome reconstitution mediated by two GTPase factors, EngA and ObgE

    Aya Sato, Weng Yu Lai ... Yoshihiro Shimizu
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Enterovirus D68 2A protease causes nuclear pore complex dysfunction and independently contributes to motor neuron toxicity

    Katrina M Zinn, Mathew W McLaren ... Matthew J Elrick
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression

    Functional Separation of mRNA Domains Coordinates Pluripotent Cell Behavior

    Ze Yang, Shaoyi Ji ... Mary A Hynes
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Incomplete
    1. Medicine
    2. Epidemiology and Global Health

    Determining fragility and robustness to missing data in binary outcome meta-analyses, illustrated with conflicting associations between vitamin D and cancer mortality

    David Robert Grimes
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    The nucleus accumbens shell regulates hedonic feeding via a rostral hotspot

    Alina-Măriuca Marinescu, Eshita Kamal ... Marie A Labouesse
    Within the nucleus accumbens shell, a spatially defined rostral subregion selectively modulates hedonic feeding, revealing functional heterogeneity in reward circuitry underlying food consumption.
    1. Immunology and Inflammation

    Lipopolysaccharide stimulates dynamic changes in B cell metabolism to promote proliferation

    Dana MS Cheung, Momchil Razsolkov ... J Simon C Arthur
    B cell activation and antibody class switching requires coordinated metabolic rewiring, with essential roles for amino acid transport, cholesterol metabolism, and prenylation in driving proliferation across multiple activating stimuli.
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