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Page 13 of 1,874
    1. Developmental Biology
    2. Genetics and Genomics

    A genome-wide MAGIC kit for recombinase-independent mosaic analysis in Drosophila

    Yifan Shen, Ann T Yeung ... Chun Han
    A comprehensive toolkit enables genome-wide, recombinase-independent mosaic analysis in Drosophila, permitting clonal analysis of pericentromeric genes, deficiency chromosomes, and interspecific hybrids previously inaccessible to standard methods.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Cell type-specific network analysis in Diversity Outbred mice identifies genes potentially responsible for human bone mineral density GWAS associations

    Luke J Dillard, Gina Calabrese ... Charles Farber
    Single-cell transcriptomics data from mouse bone-relevant cells was used to inform human bone mineral density genome-wide association studies and prioritize genetic targets with potential causal roles in the development of osteoporosis.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Multiple modes of cholesterol translocation in the human Smoothened receptor

    Prateek D Bansal, Maia Kinnebrew ... Diwakar Shukla
    Multiple competing hypotheses concerning the cholesterol accessibility of oncoprotein Smoothened are quantitatively assessed and experimentally validated, showing that cholesterol takes two pathways from either membrane leaflet to the binding sites.
    1. Neuroscience
    2. Computational and Systems Biology

    Miniscope Processing Suite (MPS): An Intuitive, No-Code, Scalable Pipeline for Long-Duration Calcium Imaging

    Ari Peden-Asarch, Meredith Weinstock ... John F Neumaier
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Butyrate rescues chlorpyrifos-induced social deficits through inhibition of class I histone deacetylases

    Leonardo Diaz, Ally Xinyi Kong ... Yijie Geng
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Circadian photoreceptor CRYPTOCHROME promotes wakefulness under short winter-like days via a GABAergic circuitry

    Lixia Chen, Danya Tian ... Luoying Zhang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Noradrenergic infraslow rhythm during sleep is the critical link between heart-rate dynamics and memory consolidation

    Sofie S Jacobsen, Allison B Morehouse ... Celia Kjaerby
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Epidemiology and Global Health

    Repurposed small molecule toxin inhibitors neutralise a diversity of venoms from the Neotropical viperid snake genus Bothrops

    Rachel H Clare, Adam Westhorpe ... Nicholas R Casewell
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Boosting Hyperalignment Performance with Age-specific Templates

    Yuqi Zhang, Maria Ida Gobbini ... Ma Feilong
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease

    Mycobacterium tuberculosis suppresses protective Th17 responses during infection

    Alex Zilinskas, Amir Balakhmet ... Sarah A Stanley
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
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