Browse the latest research

Page 13 of 1,849
    1. Medicine

    Addressing cultural and knowledge barriers to enable preclinical sex inclusive research

    Brianna N Gaskill, Benjamin Phillips ... Natasha A Karp
    Targeted education corrects key misconceptions and identifies methods to influence intent to use sex-inclusive designs in in vivo studies.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Dock-and-lock binding of SxIP ligands is required for stable and selective EB1 interactions

    Teresa Almeida, Eleanor Hargreaves ... Igor Barsukov
    Structural analysis reveals a two-step EB1-SxIP binding mechanism and identifies ligand mutations that greatly enhance affinity, offering potential therapeutic avenues for targeting microtubule plus end interactions.
    1. Microbiology and Infectious Disease

    The impact of different antimicrobial exposures on the gut microbiome in the ARMORD observational study

    Leon Peto, Nicola Fawcett ... Ann Sarah Walker
    Metagenomic sequencing of stool samples from 225 hospital patients and healthy volunteers reveals the impact of different antimicrobial exposures on the gut microbiome.
    1. Cell Biology

    Evidence of centromeric histone 3 chaperone involved in DNA damage repair pathway in budding yeast

    Prakhar Agarwal, Anushka Alekar ... Santanu K Ghosh
    Genetic and biochemical assays reveal the role of Scm3 in genome stability by regulating the DNA damage checkpoint pathway in budding yeast.
    1. Microbiology and Infectious Disease

    Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in Mycobacterium intracellulare

    Yoshitaka Tateishi, Yuriko Ozeki ... Sohkichi Matsumoto
    Revised
    Reviewed Preprint v4
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    cxcl18b-defined transitional state-specific nitric oxide drives injury-induced Müller glia cell-cycle re-entry in the zebrafish retina

    Aojun Ye, Shuguang Yu ... Chang Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Plant Biology

    Rice stripe virus utilizes a Laodelphax striatellus salivary carbonic anhydrase to facilitate plant infection by direct molecular interaction

    Jing Zhao, Xiangyi Meng ... Lili Zhang
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    DANCE: An open-source analysis pipeline and low-cost hardware to quantify aggression and courtship in Drosophila

    R Sai Prathap Yadav, Paulami Dey ... Pavan Agrawal
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

    Shuang Chen, Andrew R Mack ... Shozeb Haider
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Robust and replicable effects of ageing on resting state brain electrophysiology measured with MEG

    Andrew J Quinn, Jemma Pitt ... Mark W Woolrich
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
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