Browse the latest research

Page 13 of 1,869
    1. Structural Biology and Molecular Biophysics

    Structure of the human CTF18−RFC clamp loader bound to PCNA

    Giuseppina R Briola, Mohammad Tehseen ... Alfredo De Biasio
    Human CTF18–RFC employs a unique structural stabilization mechanism to optimize PCNA loading and stimulate DNA synthesis by the leading-strand polymerase.
    1. Neuroscience

    The influence of sample size and covariate distributions on neuroanatomical normative modeling

    Camille Elleaume, Bruno Hebling Vieira ... Nicolas Langer
    Systematic analyses show that normative model performance strongly depends on sample size and covariate distributions, larger samples yield more stable fits, while misaligned covariates introduce systematic distortions in predictions.
    1. Neuroscience

    Inverted encoding of neural responses to audiovisual stimuli reveals super-additive multisensory enhancement

    Zak Buhmann, Amanda K Robinson ... Reuben Rideaux
    A multivariate analysis of electroencephalography activity reveals super-additive enhancements to the neural encoding of audiovisual stimuli, providing new insights into how the brain integrates multisensory information to optimise spatial localisation.
    1. Medicine

    Single transcript level atlas of oxytocin and the oxytocin receptor in the mouse brain

    Vitaly Ryu, Anisa Azatovna Gumerova ... Mone Zaidi
    1. Neuroscience

    Dynamics of mesoscale brain network during visual discrimination learning revealed by chronic, large-scale single-unit recording

    Tian-Yi Wang, Chengcong Feng ... Zhengtuo Zhao
    During the acquisition of correct rejection response, rankings of functional connection separated for cortical and subcortical regions, which is predictive of the peak timing of visual information encoding across the network.
    1. Structural Biology and Molecular Biophysics

    Protein-induced membrane strain drives supercomplex formation

    Maximilian C Pöverlein, Alexander Jussupow ... Ville RI Kaila
    Respiratory supercomplex formation relieves molecular strain of mitochondrial membranes and reshapes global protein motions, linking membrane reorganization to respiratory function.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains

    Caroline Kikawa, Andrea N Loes ... Jesse D Bloom
    High-throughput measurement of neutralization titers using a new sequencing-based assay can help explain which seasonal influenza strains spread in the human population.
    1. Microbiology and Infectious Disease

    The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome

    Beth A Shen, Kyle L Asfahl ... Joseph D Mougous
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Cell Biology
    2. Neuroscience

    Death receptor 6 does not regulate axon degeneration and Schwann cell injury responses during Wallerian degeneration

    Bogdan Beirowski, Haoran Huang, Elisabetta Babetto
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology

    The insulin / IGF axis is critically important controlling gene transcription in the podocyte

    Jennifer A Hurcombe, Lusyan Dayalan ... Richard JM Coward
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid