Browse the latest research

Page 13 of 1,867
    1. Neuroscience

    Frictional instabilities as an alternative to friction coefficient in fine touch perception

    Maryanne Derkaloustian, Pushpita Bhattacharyya ... Charles B Dhong
    To study fine touch, selecting samples based on how many mechanical instabilities they can form is more predictive than using the friction coefficient, which has been the default choice.
    1. Genetics and Genomics

    SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven two-cell totipotency transcriptional program in the mouse embryo

    Tie-Bo Zeng, Zhen Fu ... Piroska E Szabó
    Conditional genetics and single-embryo RNA-seq show that SETDB1 extinguishes the transient, retroelement-driven transcriptional programs of the totipotent two-cell state to facilitate the exit from totipotency and ensure preimplantation development.
    1. Genetics and Genomics

    Visible traits demonstrate that crispant founder mice can be used for phenotypic assessment

    Rebekah Tillotson, Marina Gertsenstein ... Monica J Justice
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Cancer Biology

    The 1000+ mouse project: large–scale spatiotemporal parametrization and modeling of preclinical cancer immunotherapies

    Adam L Kenet, Sooraj Achar ... Grégoire Altan-Bonnet
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Medicine

    The inactivation of DHHC7 in mouse liver promotes diet-induced obesity through a hepatic Prg4–GPR146 axis

    Yingmin Sun, Ying Liu ... Bing Chen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology

    Trehalose metabolism regulates transcriptional control of muscle development in lepidopteran insects

    Sharada Mohite, Tanaji Devkate ... Rakesh Shamsunder Joshi
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Neuroscience

    Intravital calcium imaging of meningeal macrophages reveals niche-specific dynamics and aberrant responses to brain hyperexcitability

    Simone Carneiro-Nascimento, Chao Wei ... Dan Levy
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Trial-level Representational Similarity Analysis

    Shenyang Huang, Cortney M Howard ... Simon W Davis
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid