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    1. Cancer Biology
    2. Computational and Systems Biology

    BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment

    Emilio Rios-Jimenez, Anoek Zomer ... Maria Alieva
    BEHAV3D Tumor Profiler enables researchers without computational expertise to uncover heterogeneous cell behaviors and explore their relationships with microenvironmental features in intravital microscopy data.
    1. Ecology
    2. Physics of Living Systems

    The dominant–egalitarian transition in species-rich communities

    David A Kessler, Nadav M Shnerb
    A model of a species-rich neutral ecosystem, perturbed by environmental noise impacting each species differently, predicts that for large noise the community is dominated by a few species, while for weaker noise it is more egalitarian, with many significant species.
    1. Neuroscience

    Foveated metamers of the early visual system

    William F Broderick, Gizem Rufo ... Eero P Simoncelli
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Genetics and Genomics

    MerQuaCo: a computational tool for quality control in image-based spatial transcriptomics

    Naomi Martin, Paul Olsen ... Jack Waters
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Neuroscience

    Homeostatic synaptic plasticity of miniature excitatory postsynaptic currents in mouse cortical cultures requires neuronal Rab3a

    Andrew G Koesters, Mark M Rich, Kathrin Engisch
    The first demonstration that a protein thought to function presynaptically (Rab3a) is required for homeostatic, activity-dependent synaptic plasticity of quantal size in central neurons.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    HIF1A-mediated pathways promote euploid cell survival in chromosomally mosaic embryos

    Estefania Sanchez-Vasquez, Marianne E Bronner, Magdalena Zernicka-Goetz
    Aneuploid mosaic mouse embryos require hypoxia for survival, and understanding these pathways may inform new strategies to support embryo viability.
    1. Cell Biology

    Organelle membrane-associated proteins recruit cGAS via phase separation to facilitate its membrane localization

    Chengrui Shi, Chaofei Su ... Hang Yin
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Neuroscience

    Allocentric and egocentric cues constitute an internal reference frame for real-world visual search

    Yan Chen, Zhe-Xin Xu
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Explainable machine learning-assisted exploration of chromatin dynamics reveals chromosome-specific response to serum starvation

    Taras Redchuk, Antti Pennanen ... Maria K Vartiainen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Neuroscience
    2. Computational and Systems Biology

    Absence of Systematic Effects of Internalizing Psychopathology on Learning Under Uncertainty

    Muhammad H Satti, Katharina Wille ... Rasmus Bruckner
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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