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    1. Physics of Living Systems

    Balancing stability and flexibility when reshaping archaeal membranes

    Miguel Amaral, Felix Frey ... Anđela Šarić
    Archaeal cells mix single-headed and double-headed lipids to construct resilient but flexible membranes to help them survive in extreme environments.
    1. Neuroscience

    Distributed subthreshold representation of sharp wave-ripples by hilar mossy cells

    Ayako Ouchi, Taro Toyoizumi ... Yuji Ikegaya
    Machine learning with whole-cell patch-clamp and local field potential recordings reveals that synaptic responses from five mossy cells, despite their limited population, can significantly reconstruct about 30% of the total hippocampal sharp wave-ripples, highlighting efficient distributed coding within subthreshold activities.
    1. Neuroscience

    A unified rodent atlas reveals the cellular complexity and evolutionary divergence of the dorsal vagal complex

    Cecilia Hes, Abigail J Tomlinson ... Paul V Sabatini
    The dorsal vagal complex is a highly intricate structure composed of distinct transcriptional classes of glial and neuronal cells, exhibiting many similarities but also notable differences between mice and rats.
    1. Neuroscience

    Efficient coding explains neural response homeostasis and stimulus-specific adaptation

    Edward James Young, Yashar Ahmadian
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Oxytocin neurons signal state-dependent transitions from rest to thermogenesis and behavioral arousal in social and non-social settings

    Morgane Vandendoren, Jason G Landen ... Adam C Nelson
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Neuronal detection triggers systemic digestive shutdown in response to adverse food sources in Caenorhabditis elegans

    Yating Liu, Guojing Tian ... Bin Qi
    A neural-digestive mechanism has been presented for evaluating harmful food.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Pan-tissue transcriptome analysis reveals sex-dimorphic human aging

    Siqi Wang, Danyue Dong ... Zefeng Wang
    Widespread sex-dimorphic transcriptomic changes during human aging in pan-tissues scale reveal distinct molecular aging trajectories and potential links to age-related disease vulnerability.
    1. Neuroscience

    Optogenetic stimulation of single ganglion cells in the living primate fovea

    Peter J Murphy, Juliette E McGregor ... David R Williams
    Individual retinal ganglion cells are singularly activated in the living primate retina via an adaptive optics scanning light ophthalmoscope.
    1. Neuroscience

    Dual transcranial electromagnetic stimulation of the precuneus boosts human long-term memory

    Ilaria Borghi, Lucia Mencarelli ... Giacomo Koch
    Rapid, combined and personalized non-invasive stimulation of the precuneus improves associative memory, enhances local gamma expression, and strengthens precuneus–hippocampal connectivity.
    1. Epidemiology and Global Health
    2. Computational and Systems Biology

    Refining uncertainty about the TAK-003 dengue vaccine with a multi-level model of clinical efficacy trial data

    Manar Alkuzweny, Guido España, T Alex Perkins
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing