Browse the latest research

Page 233 of 1,790
    1. Neuroscience

    Quantitative modeling of the emergence of macroscopic grid-like representations

    Ikhwan Bin Khalid, Eric T Reifenstein ... Richard Kempter
    A computational study quantifies how macroscopic grid-like representations may emerge in the human brain using different hypotheses and navigation patterns, indicating the need to further characterize properties of grid cells.
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    MDverse, shedding light on the dark matter of molecular dynamics simulations

    Johanna KS Tiemann, Magdalena Szczuka ... Pierre Poulain
    Identifying, indexing, and annotating molecular dynamics simulations open data is essential to ensure their proper reuse.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Long-distance electron transport in multicellular freshwater cable bacteria

    Tingting Yang, Marko S Chavez ... Mohamed Y El-Naggar
    A biophysical approach sheds light on the electron transport physics and electric metabolism of centimeter-long filamentous freshwater cable bacteria.
    1. Cell Biology

    Damage-induced basal epithelial cell migration modulates the spatial organization of redox signaling and sensory neuron regeneration

    Alexandra M Fister, Adam Horn ... Anna Huttenlocher
    Isotonic treatment limits keratinocyte movement, spatially restricts reactive oxygen species production, and rescues sensory neuron function after thermal injury.
    1. Microbiology and Infectious Disease

    Polysaccharides induce deep-sea Lentisphaerae strains to release chronic bacteriophages

    Chong Wang, Rikuan Zheng ... Chaomin Sun
    Chronic bacteriophages are induced by the supplement of polysaccharide in the deep-sea Lentisphaerae strains, and these bacteriophages potentially reprogram host polysaccharide metabolism through the auxiliary metabolic genes.
    1. Microbiology and Infectious Disease

    Divergent downstream biosynthetic pathways are supported by L-cysteine synthases of Mycobacterium tuberculosis

    Mehak Zahoor Khan, Debbie M Hunt ... Vinay Kumar Nandicoori
    CysM and CysK2 play complementary and overlapping roles in Mtb's adaptation to environmental stress that are crucial for survival.
    1. Medicine

    PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy

    Teruhiko Yoshida, Khun Zaw Latt ... Jeffrey B Kopp
    Single-nuclear transcriptomic profiling and functional assays identified PKR activation and mitochondrial dysfunction in HIV-associated nephropathy mice kidneys.
    1. Cell Biology

    TRIP13 localizes to synapsed chromosomes and functions as a dosage-sensitive regulator of meiosis

    Jessica Y Chotiner, N Adrian Leu ... P Jeremy Wang
    Mouse TRIP13 localizes to synapsed chromosomal axes and thus exhibits mutually exclusive localization with HORMAD1/HORMAD2, providing a cell biological explanation for dissociation of HORMAD1/2 from chromosomal axes upon synapsis.
    1. Cell Biology

    Detection of TurboID fusion proteins by fluorescent streptavidin outcompetes antibody signals and visualises targets not accessible to antibodies

    Johanna Odenwald, Bernardo Gabiatti ... Susanne Kramer
    Proteins that are low abundant and/or poorly accessible to antibodies can be readily localised with fluorescent streptavidin, when expressed fused to a biotin ligase.
    1. Neuroscience

    Opposing actions of co-released GABA and neurotensin on the activity of preoptic neurons and on body temperature

    Iustin V Tabarean
    Preoptic neurotensinergic neurons co-release GABA and neurotensin, triggering a rapid initial inhibition followed by a sustained excitation, and mice lacking GABA release from these neurons exhibit altered thermoregulation.