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Host-directed therapy neutralizes a refined immuno-evasive maneuver of pathogenic staphylococci.

Structural neuroimaging of 40,087 individuals identifies a distinct brain morphological profile associated with metabolic syndrome, linking cardiometabolic risk to cognitive performance, microscale tissue composition, and macroscale brain network architecture.

Major cell types across various brain regions distinctively associate with tissue loss in 13 neurodegenerative conditions.

The extracellular matrix formed during embryonic brain development facilitates the migration of cortical neurons.

Dopamine and GABA neurons in the ventral tegmental area encode short-term memory in the T-maze task, which cannot be explained by reward-related processes, motivated behavior, or motor-related activities.

Quantitative protein and ribosome 'accounting' in T cells highlights a gap in our understanding of how activated T cells sufficiently replicate their proteome during rapid cell division driven by infection.

Structure–function studies on the synaptic vesicle release protein syntaxin-1 identified structural motifs on the surface of the SNARE complex controlling vesicle priming and spontaneous release unique for synaptic signaling.

Brain-wide activation patterns reveal the distinct and shared neurophysiological impacts of ketamine and isoflurane, highlighting key nuclei involved in the modulation of general anesthesia.

Visuo-auditory associative memories in the neocortex are formed through cholecystokinin-mediated heterosynaptic plasticity, primarily involving entorhinal cortex projections to the auditory cortex, highlighting intricate neural dynamics in multisensory memory processing.