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    1. Cell Biology

    STAG3 promotes exit from pluripotency through post-transcriptional mRNA regulation in the cytoplasm

    Sam Weeks, Dubravka Pezic ... Suzana Hadjur
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology

    A 2-hydroxybutyrate-mediated feedback loop regulates muscular fatigue

    Brennan J Wadsworth, Marina Leiwe ... Randall S Johnson
    The metabolite 2-hydroxybutyrate is an important aspect of exhaustion which leads to increased capacity in the branched chain amino acid degradation pathway.
    1. Genetics and Genomics

    Resetting of H3K4me2 during mammalian parental-to-zygote transition

    Chong Wang, Yong Shi ... Jiawei Xu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Structural epitope profiling identifies antibodies associated with critical COVID-19 and long COVID

    Patrick KA Kearns, Charles Dixon ... Nick Gilbert
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    Acute targeted induction of gut-microbial metabolism affects host clock genes and nocturnal feeding

    Giorgia Greter, Claudia Moresi ... Markus Arnoldini
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Stem Cells and Regenerative Medicine

    Sox9 marks limbal stem cells and is required for asymmetric cell fate switch in the corneal epithelium

    Gabriella Rice, Olivia Farrelly ... Panteleimon Rompolas
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Developmental Biology
    2. Evolutionary Biology

    Insect metamorphosis is regulated differently between sexes by members of a microRNA cluster

    Chade Li, Ki Kei Chan ... Jerome HL Hui
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    Ripply1 and Gsc collectively suppress anterior endoderm differentiation from prechordal plate progenitors

    Tao Cheng, Xiang Liu ... Peng-Fei Xu
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    BRCA1/BRC-1 and SMC-5/6 regulate DNA repair pathway engagement during Caenorhabditis elegans meiosis

    Erik Toraason, Alina Salagean ... Diana E Libuda
    To maintain genomic integrity during oocyte development, the tumor suppressor BRCA1/BRC-1 and the SMC-5/6 complex both repress intersister crossover recombination events while BRCA1/BRC-1 also specifically inhibits error prone repair of DNA breaks during meiotic prophase I.
    1. Evolutionary Biology

    The genetic architecture of the load linked to dominant and recessive self-incompatibility alleles in Arabidopsis halleri and Arabidopsis lyrata

    Audrey Le Veve, Mathieu Genete ... Vincent Castric
    By modulating the intensity of balancing selection at the S-locus, dominance between self-incompatibility alleles shapes the genetic load linked to each allele, creating inbreeding depression in some S-locus homozygotes.
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