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    1. Evolutionary Biology

    Evolution of hind limb morphology of Titanosauriformes (Dinosauria, Sauropoda) analyzed via 3D Geometric Morphometrics reveals wide-gauge posture as an exaptation for gigantism

    Adrian Paramo Blazquez, Pedro Mocho ... Francisco Ortega
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Structure and Cl- Conductance Properties of the Open State of Human CFTR

    Zhi-Wei Zeng, Christopher E Ing, Régis Pomès
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stochastic cell-intrinsic stem cell decisions control colony growth in planarians

    Tamar Frankovits, Prakash Varkey Cherian ... Omri Wurtzel
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Interplay of YEATS2 and GCDH mediates histone crotonylation and drives EMT in head and neck cancer

    Deepak Pant, Parik Kakani ... Sanjeev Shukla
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Reduced discrimination between signals of danger and safety but not overgeneralization is linked to exposure to childhood adversity in healthy adults

    Maren Klingelhöfer-Jens, Katharina Hutterer ... Tina B Lonsdorf
    Childhood adversity is associated with aberrant threat learning patterns in a large healthy adult sample as evidenced by empirically testing several theories linking childhood adversity to psychopathology.
    1. Genetics and Genomics
    2. Neuroscience

    Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology

    Monique Marylin Alves de Almeida, Yves De Repentigny ... Rashmi Kothary
    A liver-specific depletion of the survival motor neuron protein in a mouse model unveils a compelling and intricate connection between liver function and pancreatic abnormalities in spinal muscular atrophy.
    1. Medicine
    2. Microbiology and Infectious Disease

    Differences in HIV-1 reservoir size, landscape characteristics, and decay dynamics in acute and chronic treated HIV-1 Clade C infection

    Kavidha Reddy, Guinevere Q Lee ... Thumbi Ndung'u
    Extremely early antiretroviral therapy during HIV-1 subtype C infection leads to faster decline in genome-intact viruses, reduced genetic complexity, and immune escape, and may enhance reservoir clearance with additional interventional strategies.
    1. Developmental Biology

    Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis

    Igor Kondrychyn, Liqun He ... Li-Kun Phng
    Investigation of Aquaporin water channels unveils water inflow and build-up of hydrostatic pressure in endothelial tip cells as a novel mechanism of endothelial cell migration and blood vessel formation.