Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    Mechanism of barotaxis in marine zooplankton

    Luis Alberto Bezares Calderón, Réza Shahidi, Gáspár Jékely
    Ciliated zooplankton larvae sense pressure by ciliary photoreceptor cells, which increase the beating of locomotor cilia via a serotonergic motor circuit leading to rapid upward swimming during barotaxis.
    1. Neuroscience

    Laminar specificity and coverage of viral-mediated gene expression restricted to GABAergic interneurons and their parvalbumin subclass in marmoset primary visual cortex

    Frederick Federer, Justin Balsor ... Alessandra Angelucci
    The gene-regulatory enhancers h56D and S5E2 restrict transgene expression to GABAergic and parvalbumin-positive interneurons, respectively, across marmoset cortical layers, thus representing a promising tool for circuit dissection in non-human primates.
    1. Neuroscience

    Ca2+ channel and active zone protein abundance intersects with input-specific synapse organization to shape functional synaptic diversity

    Audrey T Medeiros, Scott J Gratz ... Kate M O'Connor-Giles
    In vivo analysis of endogenously tagged Ca2+ channel subunits reveals unexpected differences in subunit composition and synapse-specific relationships between channel abundance and synaptic strength.
    1. Neuroscience

    When Abstract Becomes Concrete: Naturalistic Encoding of Concepts in the Brain

    Viktor Kewenig, Gabriella Vigliocco, Jeremy I Skipper
    1. Neuroscience

    DNL343 is an investigational CNS penetrant eukaryotic initiation factor 2B activator that prevents and reverses the effects of neurodegeneration caused by the integrated stress response

    Ernie Yulyaningsih, Jung H Suh ... Pascal E Sanchez
    DNL343, a brain-penetrant integrated stress response inhibitor, reduces neurodegeneration in mouse models and identifies biomarker candidates for assessing treatment responses in clinical settings.
    1. Neuroscience

    Bidirectional dysregulation of synaptic glutamate signaling after transient metabolic failure

    Stefan Passlick, Ghanim Ullah, Christian Henneberger
    Synaptic glutamate release is potentiated by short metabolic failure whereas longer durations of energy depletion lead to a postsynaptic failure of synaptic transmission.
    1. Neuroscience

    Cell-type-specific origins of locomotor rhythmicity at different speeds in larval zebrafish

    Moneeza A Agha, Sandeep Kishore, David L McLean
    Unexpected complexity in the synaptic basis of locomotor rhythmogenesis is linked to cell type and speed in larval zebrafish.

Highlights

    1. Neuroscience

    Stopping runaway seizures

    Gordon F Buchanan
    1. Neuroscience

    Movement: Planning ahead

    Raeed H Chowdhury

Senior editors

  1. Merritt Maduke
    Stanford University School of Medicine, United States
  2. Lois Smith
    Harvard Medical School, Children's Hospital Boston, United States
  3. Kenton J Swartz
    National Institute of Neurological Disorders and Stroke, NIH, United States
  4. See more editors