Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    Modeling the prodromal phase of Alzheimer’s disease: Selective amyloid-driven failure of cholinergic medial septal neurons perturbs REM sleep, cognition, emotion, and broadcasts pathology in aging mice

    Mathieu Nollet, Wei Ba ... William Wisden
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Social Influence in Donation Behavior: The Effect of Mean, Variance, and Psychopathy

    Tao Jin, Shen Zhang ... Iris Vilares
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    α/β-Hydrolase domain-containing 6 (ABHD6) accelerates the desensitization and deactivation of TARP γ-2-containing AMPA receptors

    Rixu Cong, Huiran Li ... Chen Zhang
    The gating kinetics of AMPARs are regulated by ABHD6 in a TARP γ-2-dependent manner.
    1. Neuroscience

    Economic and social modulations of innate decision-making in mice exposed to visual threats

    Zhe Li, Jiahui Wang ... Ya-tang Li
    Threat, reward, and social hierarchy jointly shape innate defensive decisions through vigilance-dependent value integration.
    1. Neuroscience

    Local inhibitory dynamics underpin temporal integration and functional segregation between barrels and septa in the mouse barrel cortex

    Ali Özgür Argunşah, Tevye Jason Stachniak ... Theofanis Karayannis
    Elfn1-mediated synaptic facilitation onto somatostatin-positive interneurons drives the local lateral inhibition required to functionally segregate cortical barrel and septal processing domains in mice.
    1. Neuroscience

    A single evidence accumulation process informs perceptual choices and subsequent confidence reports

    John P Grogan, Luc Vermeylen ... Redmond G O’Connell
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    cuBNM: GPU-Accelerated Brain Network Modeling

    Amin Saberi, Bin Wan ... Sofie L Valk
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    The digital sphinx: Can a worm brain control a fly body?

    Bingni W Brunton, Elliott TT Abe ... John C Tuthill
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    A behavioral architecture for realistic simulations of Drosophila larva locomotion and foraging

    Panagiotis Parthenios Sakagiannis, Anna-Maria Jürgensen, Martin Paul Nawrot
    A three-layered modular architecture unifies diverse computational models of Drosophila larval behavior, enabling realistic closed-loop simulations from locomotion through chemotaxis to associative learning.
    1. Neuroscience

    Visual Categorization: How monkeys carve up the visual world

    Binxu Wang
    Monkeys generalize many visual categorization rules, such as animate versus inanimate, but fail on culturally defined ones, placing their behavior closer to networks trained on images alone than to humans.
    Version of Record
    Insight
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Highlights

    1. Neuroscience
    Image credit: geralt (CC0)

    Understanding the cellular architecture of Huntington’s disease

    Dorian Pustina
    1. Neuroscience
    Merrilee Schultz (CC0 via unsplash)

    Stronger memories through smarter stimulation

    Justin Riddle
    1. Neuroscience

    Language acquisition in newborns

    Marcela Peña

Senior editors

  1. Albert Cardona
    University of Cambridge, United Kingdom
  2. Joshua I Gold
    University of Pennsylvania, United States
  3. Ma-Li Wong
    State University of New York Upstate Medical University, United States
  4. See more editors