Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    Accumulation of neural state transitions in dorsomedial striatum predicts patch foraging decisions

    Elissa Sutlief, Shichen Zhang ... Marshall G Hussain Shuler
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Characterising semantic prioritisation in visual working memory

    Casper Kerrén, Carlos González-García, Juan Linde-Domingo
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Adaptive behavior is guided by integrated representations of controlled and non-controlled information

    Bingfang Huang, Harrison Ritz, Jiefeng Jiang
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Mood computational mechanisms underlying increased risk behavior in adolescent suicidal patients

    Zhihao Wang, Tian Nan ... Bastien Blain
    Adolescent suicidality is linked to riskier choices through stronger attraction to high-reward gambles and blunted mood responses to safe rewards.
    1. Neuroscience

    Functional specialization of mPFC-BLA and mPFC-NAc pathways in affective state representation

    Chien-Hsien Lai, Gyeongah Park ... Jianyang Du
    Separate prefrontal output channels preferentially track anxiety, exploration, and social preference, revealing how emotional context is organized into adaptive behavior.
    1. Neuroscience

    LRRK2 regulates synaptic function through modulation of actin cytoskeletal dynamics

    Giulia Tombesi, Shiva Kompella ... Elisa Greggio
    LRRK2 couples brain-derived neurotrophic factor (BDNF) signaling to synaptic actin remodeling, defining a novel mechanism of LRRK2 synaptic function and highlighting early, targetable pathways in Parkinson’s disease.
    1. Neuroscience

    Brainstem neurons coordinate the bladder and urethral sphincter for urination

    Xing Li, Xianping Li ... Jiwei Yao
    Estrogen receptor 1 (ESR1)-positive neurons in the pontine micturition center govern detrusor–sphincter coordination via three distinct spinal projections, representing a therapeutic target for detrusor–sphincter dyssynergia and associated voiding dysfunction.
    1. Neuroscience

    Distinct neural representations of perceptual and numerical absence in the human brain

    Benjy Barnett, Stephen M Fleming
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    An integrated human forebrain organoid reveals microglia-mediated CD8+ T cell recruitment and neuroimmune dysfunction in Alzheimer’s disease pathology

    Yilin Feng, Feifei Yu ... Shaohua Ma
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Simple Methods to Acutely Measure Multiple Timing Metrics among Sexual Repertoire of Male Drosophila

    Yutong Song, Hongyu Miao ... Woo Jae Kim
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
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Highlights

    1. Neuroscience
    Image credit: geralt (CC0)

    Understanding the cellular architecture of Huntington’s disease

    Dorian Pustina
    1. Neuroscience
    Merrilee Schultz (CC0 via unsplash)

    Stronger memories through smarter stimulation

    Justin Riddle
    1. Neuroscience

    Language acquisition in newborns

    Marcela Peña

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Andrew J King
    Andrew J King
    University of Oxford, United Kingdom
  3. Sonia Q Sen
    Tata Institute for Genetics and Society, India
  4. See more editors