Neuroscience

Neuroscience

eLife reviews research including brain function, neuronal circuits, synapses, sensory processing and motor pattern generation. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Neuroscience

    Spine nanostructure profiling of cultured neurons from mouse models reveals a schizophrenia-linked role for Ecrg4

    Yutaro Kashiwagi, Qingrui Liu ... Shigeo Okabe
    Population-level analysis of dendritic spine nanostructure identifies distinct synaptic signatures of schizophrenia and autism, revealing Ecrg4 as a regulator of schizophrenia-associated spine pathology.
    1. Neuroscience

    In vivo mapping of striatal neurodegeneration in Huntington’s disease with Soma and Neurite Density Imaging

    Vasileios Ioakeimidis, Marco Palombo ... Claudia Metzler-Baddeley
    Novel SANDI diffusion modelling reveals Huntington’s disease-related striatal abnormalities in proxy soma measures, explaining atrophy and motor impairment, and supporting SANDI indices as in vivo biomarkers of human neurodegenerative processes.
    1. Neuroscience

    Distinct sensorimotor encoding in tuft dendrites and somata associated with action, correction, and learning

    Jackson Scheib, Zachary L Newman ... Aaron Kerlin
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Noradrenergic infraslow rhythm during sleep is the critical link between heart-rate dynamics and memory consolidation

    Sofie S Jacobsen, Allison B Morehouse ... Celia Kjaerby
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Adaptive behavior is guided by integrated representations of controlled and non-controlled information

    Bingfang Huang, Harrison Ritz, Jiefeng Jiang
    Revised
    Reviewed Preprint v4
    Updated
    • Useful
    • Solid
    1. Neuroscience

    Accumulation of neural state transitions in dorsomedial striatum predicts patch foraging decisions

    Elissa Sutlief, Shichen Zhang ... Marshall G Hussain Shuler
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Characterising semantic prioritisation in visual working memory

    Casper Kerrén, Carlos González-García, Juan Linde-Domingo
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Mood computational mechanisms underlying increased risk behavior in adolescent suicidal patients

    Zhihao Wang, Tian Nan ... Bastien Blain
    Adolescent suicidality is linked to riskier choices through stronger attraction to high-reward gambles and blunted mood responses to safe rewards.
    1. Neuroscience

    Functional specialization of mPFC-BLA and mPFC-NAc pathways in affective state representation

    Chien-Hsien Lai, Gyeongah Park ... Jianyang Du
    Separate prefrontal output channels preferentially track anxiety, exploration, and social preference, revealing how emotional context is organized into adaptive behavior.
    1. Neuroscience

    LRRK2 regulates synaptic function through modulation of actin cytoskeletal dynamics

    Giulia Tombesi, Shiva Kompella ... Elisa Greggio
    LRRK2 couples brain-derived neurotrophic factor (BDNF) signaling to synaptic actin remodeling, defining a novel mechanism of LRRK2 synaptic function and highlighting early, targetable pathways in Parkinson’s disease.

Senior editors

  1. Timothy Behrens
    University of Oxford / University College London, United Kingdom
  2. Tamar Makin
    University College London, United Kingdom
  3. Kate Wassum
    University of California, Los Angeles, United States
  4. See more editors