Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Cauã Antunes Westmann, Leander Goldbach, Andreas Wagner
Across three global Escherichia coli regulators, identical starting sequences can evolve toward many distinct strong-binding peaks, with chance, historical contingency, and evolutionary bias shaping which outcomes prevail.
Nicholas A Bates, Ronald Rodriguez ... Bennett H Penn
Antibiotics that inhibit translation cause a burst in reactive oxygen species, and these must be detoxified by factors such as KatG for cells to survive.
Morena Raiola, Miquel Sendra Sendra ... Miguel Torres
A computational pipeline leverages mammalian heart development videos to extract tissue deformation patterns and generate a virtual fate map tool that provides new insights into cardiac morphogenesis.
Revathi Balasubramanian, Nicholas Tolman ... Simon WM John
High-resolution single-cell transcriptomics reveals the molecular programs and signaling networks driving Schlemm's canal and trabecular meshwork development, establishing a foundation for understanding glaucoma pathogenesis.
Explaining the neural mechanisms underlying language-based, spontaneous categorization of visual words of alphabetic and non-alphabetic languages by combining electroencephalography, magnetoencephalography, and a repetition suppression paradigm.
A single temporal integration process links momentary perceptual biases to the generalization of learned skills, providing a unifying account of specificity versus flexibility in human learning.
Reducing vertical forces reveals kinesin-1 as a robust motor capable of sustaining high loads and efficiently generating large collective forces with multiple motors.