Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Endophilin-A3-mediated clathrin-independent endocytosis and retrograde trafficking in cancer cells regulate ICAM1 organization at the immune synapse and influence cytotoxic CD8 T cell response.
Andrés Pablo Varani, Caroline Mailhes-Hamon ... Daniela Popa
Distinct cerebellar projections to the forebrain differentially support acquisition and offline consolidation of a motor skill engaging cerebello-striato-cortical circuits, revealing the temporal and functional diversity of cerebellar contributions to learning.
Harikrishnan Rajendran, Roi Weinberger ... Ofer Feinerman
The architecture of an ant nest serves as a fossilized record of the colony's demographic history, with distinct growth patterns and catastrophic events through age-specific digging behaviors.
A scalable zebrafish imaging platform reveals that Foxp1 paralogues have non-redundant roles in developmental patterning of adipose morphology and adaptive remodelling capacity in response to a high-fat diet.
A velocity-nulled 3T GE-EPI fMRI method enabling 0.9-mm whole-brain imaging that suppresses vascular contamination and reliably maps layer-specific functional connectivity in human cortex.
Colin Bredenberg, Fabrice Normandin ... Guillaume Lajoie
Computational simulations indicate that classical psychedelics could induce hallucinations by co-opting neural circuitry dedicated to sleep-dependent replay and consolidation, providing a theoretical link between seemingly disparate fields of inquiry.
Rats with a history of cocaine use exhibited prolonged encoding of idiosyncratic task features in orbitofrontal cortex and a reduced ability to compress such features to identify underlying hidden states.