Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Hengqi Betty Zheng, Benjamin A Doran ... Leslie S Kean
Single-cell profiling of untreated pediatric Crohn’s disease identifies coordinated immune and epithelial cell states that stratify patients by disease severity and future anti-TNF response.
Jonathan Reinwald, Sarah Ghanayem ... Wolfgang Kelsch
Automated, long-term tracking reveals that social rank in male mice is a stable individual trait that persists across group changes, with chasing serving to negotiate rank among dominant individuals.
SETD6-mediated methylation of PPARγ establishes a positive feedback mechanism that enhances transcriptional activation and promotes hepatic lipid accumulation.
Sofie S Jacobsen, Allison B Morehouse ... Celia Kjaerby
Very-low-frequency heart rate variability reflects locus coeruleus activity during sleep and predicts spindle-dependent memory consolidation across mice and humans.
Envelope-carrying Ty3/gypsy LTR retrotransposons are ancient and widespread across animals, revealing deep evolutionary links between retroelements, viral fusogens, and retroviruses.
Niels Janssen, Uriel KA Elvira ... Theo GM van Erp
Time-resolved mapping of whole-brain functional MRI networks during human emotional experience reveals a dynamic systems-level organization that links temporal processing with large-scale functional brain architecture.
Meta Dynamic Network analysis can identify the capacity of a network to facilitate adaptive drug resistance and the respective underlying mechanistic causes.
Sideways locomotion in true crabs likely originated once from a forward-moving ancestor, providing insight into how behavioral innovations shape evolutionary diversification.
