Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Zenith D Rudich, Jiaxi Guan ... Jeremy M Van Raamsdonk
Comparing gene expression across a panel of nine long-lived mutants in a single study reveals that these mutants utilize both common and unique genetic strategies to achieve long life.
Foveal attentional processing coordinates with peripheral attention to dynamically shape global attention allocation and fixation behavior during active vision.
Hélène Vantomme, Valentin Quiniou ... David Klatzmann
Sex-specific biases in thymic T cell receptor selection enrich female CD8 T cell repertoires for autoimmunity-associated self-antigens, helping explain women’s increased susceptibility to autoimmune diseases.
Magdalena Solyga, Marek Zelechowski, Georg B Keller
Visuomotor mismatch events elicit robust human prediction error responses that exceed conventional oddball mismatch negativity, enabling translation of sensorimotor prediction mechanisms from mice to humans.
Andrew C Glover, Hannah Koenker ... Thomas S Churcher
While transmission intensity should still drive where insecticide-treated nets are prioritised, deprioritising areas where people are more likely to use nets may cause larger case resurgences than otherwise expected.
Anastasios Marantos, Kim Sneppen ... Namiko Mitarai
Energy-limited bacterial cells reduce phage adsorption, particularly for weakly binding viruses, revealing host physiology as a key factor in viral commitment to infection.
Spontaneous reactivation of an interrupted biosynthetic gene reveals unexpected plasticity in folate-dependent one-carbon metabolism that promotes growth and virulence in the foodborne human pathogen Listeria monocytogenes.
Brain activity in the pre-supplementary motor area and dorsolateral prefrontal cortex represents gaze-weighted accumulated evidence signals in value-based decision-making.
MOTS-c, a mitochondrial-encoded microprotein, has immunological origins and functions, revealing for the first time that our immune system is encoded by both co-evolved nuclear and mitochondrial genomes.