Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Christopher Peterson, Joshua Miller ... Vitaly V Ganusov
Cooperation between individual virions of human cytomegalovirus at infecting cells leads to nonlinear scaling of cell infection probability with virion concentration.
Patrick B Jonker, Mumina Sadullozoda ... Alexander Muir
Modeling the metabolic microenvironment of pancreatic tumors leads to the identification of polyunsaturated fatty acid metabolism as a vulnerability of pancreatic cancer.
Age-specific templates improve the quality of functional alignment using hyperalignment algorithms, and the improvement is consistent across age groups, validation analyses, and datasets.
Face-selective neural activity occurs concurrently across the human ventral occipito-temporal cortex, challenging traditional hierarchical models of visual object recognition where response latencies increase along the cortical hierarchy.
Heterogeneity in outcomes of differently located activating mutations of Notch indicates the need and potential for mutant specific targeting of Notch in cancer.
Leiomodin 1 acts as a critical molecular switch during early muscle stem cell differentiation by sequestering the deacetylase SIRT1 in the cytoplasm to initiate the myogenic program.
David C Gruskin, Daniel J Vieira ... Gaurav H Patel
Genetic influences on how the brain processes complex naturalistic stimuli can be traced back to inherited control over stable spatial and temporal features of brain function.
Samantha Rose Golf, Justin H Trotter ... Thomas C Südhof
Genetic deletions in mouse models and human neuron co-cultures reveal that astrocytic neuroligins are dispensable for synapse formation and maintenance of normal astrocyte morphology, suggesting neuroligins serve alternative, unidentified roles.
In-situ glial cell-surface proteomics reveals DIP-β as a glial longevity factor that enhances intercellular communication and extends lifespan in aging Drosophila.
