Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Fangfang Hong, Ruby Bouhassira ... David H Brainard
Leveraging the smooth variation of internal noise makes comprehensive characterization of color discrimination practical, offering an efficient framework for studying perceptual limits across various sensory domains.
Rachel H Clare, Adam Westhorpe ... Nicholas R Casewell
Despite the variation in venom across the Bothrops snake genus, repurposed drugs demonstrated pan-species neutralisation in enzymatic, coagulation, and haemorrhage assays, highlighting their value as novel therapies for Neotropical snakebites.
Hidden outward-facing intermediates and long-lived ATP-bound states reveal how ATP binding drives conformational dynamics in the heterodimeric ABC transporter TmrAB.
Hanane Hadj-Moussa, Megan Ulusan ... Jonathan Houseley
Re-engineering a highly conserved metabolic pathway in yeast prevents age-related functional decline and proves that ageing is not inevitably linked to loss of fitness.
Inflammatory activation of endothelial cells triggers Pink1-dependent mitophagy and mitochondrial formyl peptides release, which drives neutrophil recruitment and lung injury.
Fundamental distinctions in the extracellular signatures of active-dendritic chemical and electrical synapses necessitate a revision of conventional interpretations of local field potentials centered on chemical synapses.
A time-dependent genetic interaction between the µ opioid receptor and genes drives early morphine responses in mice, highlighting pathways linked to human substance use disorder.
Gaze patterns during value-based choice may reflect post-decision processes rather than a direct causal influence of attention on preference formation.