Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Yaeram Jeong, Chung-ha O Davis ... Nicholas Marsh-Armstrong
Increased transfer of axonal mitochondria to optic nerve astrocytes after expression of glaucoma-associated Optineurin variants suggest that increased transcellular degradation of axonal mitochondria may play a causative role in at least some forms of glaucoma.
Ultrasound localization microscopy in awake mice enables high-resolution imaging of cerebral microvasculature in a natural physiological state, eliminates confounding effects of anesthetics, and supports reliable longitudinal vascular assessment across weeks.
Joséphine Ledamoisel, Bruno Buatois ... Violaine Llaurens
Ecological interactions exert contrasting evolutionary pressures on sympatric Morpho butterflies, promoting convergence in iridescence but divergence in chemical cues, illustrating how ecological interactions mediate trait evolution and sister-species coexistence.
Dopamine midbrain neurons surviving a lesion slowly recover their in vivo firing patterns by homeostatic pacemaker acceleration mediated by Kv4.3 channel downregulation.
Marco Garbelli, Stephanie Niklaus, Stephan CF Neuhauss
Loss of the glutamate transporters EAAT5b and EAAT7 disrupts wavelength-specific visual processing and UV-dependent prey detection in zebrafish, revealing their key roles in modulating light integration and behaviorally relevant vision.