Figure 1—figure supplement 2. | Admixture into and within sub-Saharan Africa

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Admixture into and within sub-Saharan Africa

Figure 1—figure supplement 2.

Affiliation details

Wellcome Trust Centre for Human Genetics, United Kingdom; Wellcome Trust Sanger Institute, United Kingdom; Medical Research Council Unit, The Gambia; Royal Victoria Teaching Hospital, The Gambia; Centre National de Recherche et de Formation sur le Paludisme, Burkina Faso; University of Rome La Sapienza, Italy; Navrongo Health Research Centre, Ghana; Komfo Anokye Teaching Hospital, Ghana; University of Buea, Cameroon; KEMRI-Wellcome Trust Research Programme, Kenya; Kilimanjaro Christian Medical College, Tanzania; London School of Hygiene and Tropical Medicine, United Kingdom; College of Medicine, University of Malawi, Malawi; University of Bamako, Mali
Figure 1—figure supplement 2.
Download figureOpen in new tabFigure 1—figure supplement 2. An example of hierarchical clustering to chose two groups of similar individuals from the Fula based on a PCA of The Gambia.

Projected onto a PCA of Gambian genetic variation where each point represents an individual, all Fula individuals are coloured, with the colour depicting their cluster assignment, based on the MClust clustering algorithm. We chose individuals from the green (D) and light blue (E) clusters to maximise the representation of Fula genetic variation. Note that the majority of the individuals from the other 6 Gambian ethnic groups occur in the right arm of the PCA. An analogous process was performed for all ethnic groups from the MalariaGEN dataset where more than 50 individuals were available.

DOI: http://dx.doi.org/10.7554/eLife.15266.006