Figure 3—figure supplement 5. | Admixture into and within sub-Saharan Africa

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Admixture into and within sub-Saharan Africa

Figure 3—figure supplement 5.

Affiliation details

Wellcome Trust Centre for Human Genetics, United Kingdom; Wellcome Trust Sanger Institute, United Kingdom; Medical Research Council Unit, The Gambia; Royal Victoria Teaching Hospital, The Gambia; Centre National de Recherche et de Formation sur le Paludisme, Burkina Faso; University of Rome La Sapienza, Italy; Navrongo Health Research Centre, Ghana; Komfo Anokye Teaching Hospital, Ghana; University of Buea, Cameroon; KEMRI-Wellcome Trust Research Programme, Kenya; Kilimanjaro Christian Medical College, Tanzania; London School of Hygiene and Tropical Medicine, United Kingdom; College of Medicine, University of Malawi, Malawi; University of Bamako, Mali
Figure 3—figure supplement 5.
Download figureOpen in new tabFigure 3—figure supplement 5. Results of MALDER for all populations using a European specific recombination map.

We used MALDER to identify the evidence for multiple waves of admixture in each population. (A) For each population, we show the ancestry region identity of the two populations involved in generating the MALDER curves with the greatest amplitudes (which are the closest to the true admixing sources amongst the reference populations) for at most two events. The sources generating the greatest amplitude are highlighted with a black box. Populations are ordered by ancestry of the admixture sources and dates estimates which are shown ± 1 s.e. (B) Comparison of dates of admixture ± 1 s.e. for MALDER dates inferred using the HAPMAP recombination map and a recombination map inferred from European (CEU) individuals from Hinch et al. (2011). We only show comparisons for dates where the same number of events were inferred using both methods. Point symbols refer to populations and are as in Figure 1. (C) as (B) but comparing with an African (YRI) map.

DOI: http://dx.doi.org/10.7554/eLife.15266.023