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    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Scientists reveal how the immune system helps fight hantaviruses

    A study shows for the first time how antibodies can prevent hantavirus infection, with findings that may lead to new treatment and prevention strategies.
    1. Cell Biology
    2. Medicine

    New drug combination could improve glucose and weight control in diabetes

    Adding an experimental cancer drug to a widely used diabetes medicine enhances glucose management and weight control in mice.
    1. Genetics and Genomics

    Manipulating a metabolic pathway extends lifespan in fruit flies

    Scientists have identified a metabolic pathway associated with aging and mitochondrial dysfunction in fruit flies, and show that downregulation of this pathway can extend lifespan.
    1. Cell Biology

    Reducing proton leak restores function in aging heart cells

    Blocking proton leaks in mitochondria via a crucial mitochondrial transport protein can rejuvenate aging heart cells and helps reverse aging heart dysfunction.
  1. eLife supports PREreview’s new peer review mentoring program for early-career researchers

    The two initiatives are collaborating on a project by PREreview to help instruct and support early-career researchers in scholarly review.
    1. Evolutionary Biology

    Primitive fish fossils reveal developmental origins of teeth

    High-resolution X-ray imaging of primitive bony fish fossils reveal the developmental and evolutionary relationship between teeth and dermal odontodes.
    1. Evolutionary Biology
    2. Genetics and Genomics

    How a tiny tomato pest miniaturises its genome

    Scientists have characterised the genome of a tiny tomato mite – the smallest arthropod genome reported to date.
    1. Immunology and Inflammation

    Drug may boost vaccine responses in older adults

    A preliminary study shows that a drug which helps immune cells self-clean may improve vaccine protection in older adults.
    1. Microbiology and Infectious Disease

    Scientists shed new light on how lung bacteria defend against pneumonia

    Findings suggest that probiotics could be an alternative to antibiotics for treating pneumonia and other respiratory illnesses.
  2. eLife shifting to exclusively reviewing preprints

    Open-access journal is moving to a ‘publish, then review’ model that emphasises preprints and public reviews.