A new autoencoder-based genotype imputation method shows superior accuracy across human genomes of diverse ancestry and across the allele-frequency spectrum, while delivering significantly faster inference run times relative to standard imputation tools.

Seminal fluid harbours the as yet unknown mechanism that facilitates rapid adjustment of sperm velocity in response to changing sperm competition risk.

In models reconstructed from MRI scans of patients with embolic stroke of undetermined source, computational simulations reveal that fibrosis has the intrinsic capacity to sustain arrhythmia drivers when subjected to triggered activity known to exist in patients with atrial fibrillation.

Spike frequency adaptation provides spiking neural networks with long short-term memory.

Mechanical competition is controlled by biophysical parameters that regulate cellular homeostatic density, while biochemical competition is regulated by parameters that influence the organisation of cells in a tissue.

Behavioural evidence and computational analyses suggest that people tend to decline the pursuit of more rewarded goals because they, wrongly, expect them to require more effortful actions.

A simple model provides an accessible framework to infer macroscopic parameters of effective resource competition from longitudinal studies of microbial communities.

A computational and translational approach to measuring anxiety-related behaviour was validated in two large independent samples, presenting opportunities for cross-species anxiety research and potential implications for anxiolytic drug development.

Four stages of linear and nonlinear computations in hierarchical dynamic brain networks progressively transform the same two visual inputs into the task-specific XOR, AND, and OR behavioral responses.

Genome editing, advanced live-cell microscopy, and computational modeling were combined to measure WNT/CTNNB1 signaling parameters at the single molecule level, revealing critical regulatory nodes in this important signal transduction pathway.