2,895 results found
    1. Computational and Systems Biology

    Evolutionary dynamics of incubation periods

    Bertrand Ottino-Loffler, Jacob G Scott, Steven H Strogatz
    Evolutionary graph theory solves the longstanding puzzle of why diverse infectious diseases and cancers show similar (approximately lognormal) distributions of their incubation periods.
    1. Neuroscience

    Temporal transitions of spontaneous brain activity

    Zhiwei Ma, Nanyin Zhang
    Analysis of resting-state fMRI data revealed nonrandom temporal transitions between spontaneous brain activity patterns in both awake rats and humans.
    1. Ecology
    2. Physics of Living Systems

    Spatial dilemmas of diffusible public goods

    Benjamin Allen, Jeff Gore, Martin A Nowak
    A simple model reveals the roles of colony geometry and diffusion rate in allowing microbes to cooperate by sharing public goods.
    1. Computational and Systems Biology
    2. Neuroscience

    Discovering and deciphering relationships across disparate data modalities

    Joshua T Vogelstein, Eric W Bridgeford ... Cencheng Shen
    Multiscale Graph Correlation, an interpretable hypothesis test with strong theoretical guarantees for discerning relationships in complex data, requires about half the sample size as other methods, whilst maintaining computational tractability.
    1. Computational and Systems Biology
    2. Neuroscience

    A simple generative model of the mouse mesoscale connectome

    Sid Henriksen, Rich Pang, Mark Wronkiewicz
    A realistic model of the connections between local populations of neurons in the adult mouse brain can be constructed based on just two biologically plausible rules.
    1. Neuroscience

    Non-linear dimensionality reduction on extracellular waveforms reveals cell type diversity in premotor cortex

    Eric Kenji Lee, Hymavathy Balasubramanian ... Chandramouli Chandrasekaran
    WaveMAP is a novel approach that combines nonlinear dimensionality reduction with graph clustering on extracellular waveforms to reveal previously obscured cell type diversity in monkey cortex.
    1. Neuroscience

    Temporally delayed linear modelling (TDLM) measures replay in both animals and humans

    Yunzhe Liu, Raymond J Dolan ... Timothy E Behrens
    Temporally delayed linear modelling provides a domain-general linear framework for sequence detection and statistical testing, and is able to detect replays in both human neuroimaging and animal electrophysiology.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

    Luka Bacic, Guillaume Gaullier ... Sebastian Deindl
    Analysis of conformational heterogeneity in cryo-EM data by a recently developed deep learning method reveals the structure and dynamics of the oncogenic chromatin remodeler ALC1 bound to a poly-ADP-ribosylated nucleosome.
    1. Neuroscience

    Large-scale network integration in the human brain tracks temporal fluctuations in memory encoding performance

    Ruedeerat Keerativittayayut, Ryuta Aoki ... Kiyoshi Nakahara
    Graph analysis revealed that spontaneous fluctuations of episodic-memory encoding performance associate with time-varying brain connectivity networks.
  1. Cutting Edge: A network approach to mixing delegates at meetings

    Federico Vaggi, Tommaso Schiavinotto ... Attila Csikász-Nagy
    A network-based ‘speed dating’ approach can promote interactions between delegates at scientific meetings.

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