291 results found
    1. Cell Biology
    2. Developmental Biology

    Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3

    Jarrett Smith, Deepika Calidas ... Geraldine Seydoux
    A competition for RNA drives the localized assembly of RNA granules in the C. elegans embryo.
    1. Cell Biology
    2. Developmental Biology

    Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans

    Jennifer T Wang, Jarrett Smith ... Geraldine Seydoux
    The MEG (maternal-effect germline defective) proteins, MEG-1, 2, 3 and 4, regulate RNA granule dynamics in vivo.
    1. Cell Biology
    2. Developmental Biology

    Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins

    Chih-Yung S Lee, Andrea Putnam ... Geraldine Seydoux
    The intrinsically-disordered protein MEG-3 recruits mRNAs to P granules by forming gel-like condensates with ribosome-depleted mRNAs.
    1. Neuroscience

    Lamina-specific cortical dynamics in human visual and sensorimotor cortices

    James J Bonaiuto, Sofie S Meyer ... Sven Bestmann
    Cortical oscillations in human MEG are lamina-specific, with low-frequency activity predominating in deep, and high-frequency activity in more superficial layers of sensory and motor cortices.
    1. Computational and Systems Biology

    The bottom-up and top-down processing of faces in the human occipitotemporal cortex

    Xiaoxu Fan, Fan Wang ... Sheng He
    Both bottom-up and top-down processing are involved in the occipital-temporal face network, with the top-down modulation more extensively engaged when available information is sparse in the face images.
    1. Cell Biology
    2. Developmental Biology

    Protein-based condensation mechanisms drive the assembly of RNA-rich P granules

    Helen Schmidt, Andrea Putnam ... Geraldine Seydoux
    P granule assembly depends in part on protein-protein interactions that drive condensation independent of RNA.
    1. Neuroscience

    Fast transient networks in spontaneous human brain activity

    Adam P Baker, Matthew J Brookes ... Mark Woolrich
    Non-invasive MEG recordings reveal that patterns of spontaneous activity in the resting brain are shorter lived than previously thought.
    1. Neuroscience

    Multivariate cross-frequency coupling via generalized eigendecomposition

    Michael X Cohen
    A novel methodological framework for cross-frequency coupling and spike-field coherence in multichannel (LFP, EEG, MEG) electrophysiology data reveals new manifestations of coupling dynamics.
    1. Cell Biology
    2. Developmental Biology

    Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

    Patricia Giselle Cipriani, Olivia Bay ... Kristin C Gunsalus
    Two novel LOTUS-domain proteins are core germ granule components that directly recruit Caenorhabditis elegans Vasa, regulate germ granule size and localization, and provide an organizational framework for ribonucleoprotein complexes.
    1. Neuroscience

    Testing sensory evidence against mnemonic templates

    Nicholas E Myers, Gustavo Rohenkohl ... Mark G Stokes
    Visual search templates are reactivated only temporarily to act as input filters for target detection.

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