123 results found
    1. Ecology
    2. Epidemiology and Global Health

    Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence

    Cara E Brook, Mike Boots ... Anieke van Leeuwen
    Bats' uniquely robust innate antiviral immune defenses select for faster transmitting viruses likely to generate extreme virulence upon spillover to secondary hosts with immune systems divergent from those of bat.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Updates to the zoonotic niche map of Ebola virus disease in Africa

    David M Pigott, Anoushka I Millear ... Simon I Hay
    Building on previous work (Pigott et al. 2014), estimates of areas of potential transmission of Ebola virus are revised and updated to provide a contemporary map for use by researchers and policymakers.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Mapping the zoonotic niche of Ebola virus disease in Africa

    David M Pigott, Nick Golding ... Simon I Hay
    Understanding where future Ebola virus outbreaks may start and the changing nature of the populations living in these places is of critical importance in helping to prepare for future outbreaks.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Primate malarias as a model for cross-species parasite transmission

    Marina Voinson, Charles L Nunn, Amy Goldberg
    Ecological and evolutionary perspectives are critical to understand, predict, prevent, and treat malaria parasites that may spread to humans from our close primate relatives.
    1. Ecology
    2. Epidemiology and Global Health

    Tracking zoonotic pathogens using blood-sucking flies as 'flying syringes'

    Paul-Yannick Bitome-Essono, Benjamin Ollomo ... Christophe Paupy
    A field study coupled with a molecular analysis demonstrates that using hematophagous flies as 'flying syringes' could be used to investigate blood-borne pathogen diversity in wild vertebrates and act as an early detection tool of zoonotic pathogens.
    1. Epidemiology and Global Health

    Linking rattiness, geography and environmental degradation to spillover Leptospira infections in marginalised urban settings: An eco-epidemiological community-based cohort study in Brazil

    Max T Eyre, Fábio N Souza ... Federico Costa
    While flooding events may drive spillover transmission of Leptospira spp. through dispersal of the bacteria at low elevations, at higher elevations environmental risk is more localised and directly driven by the distribution of local rat reservoir populations.
    1. Epidemiology and Global Health

    Local human movement patterns and land use impact exposure to zoonotic malaria in Malaysian Borneo

    Kimberly M Fornace, Neal Alexander ... Chris Drakeley
    Local human movement into mosquito habitats around forest edges intensifies interactions between pathogens, insects and people, increasing exposure risks to the zoonotic malaria Plasmodium knowlesi in Malaysian Borneo.
    1. Microbiology and Infectious Disease

    Co-circulation of multiple influenza A reassortants in swine harboring genes from seasonal human and swine influenza viruses

    Pia Ryt-Hansen, Jesper Schak Krog ... Lars Erik Larsen
    The abundance and complex genetic diversity of swIAV were documented and the zoonotic potential evaluated.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research

    Franziska Mohring, Melissa Natalie Hart ... Robert William Moon
    Optimised genome editing in P. knowlesi enables transgenic expression of a lead P. vivax vaccine candidate, revealing roles in host cell tropisms and providing tools for scalable vaccine efficacy testing.
    1. Ecology
    2. Epidemiology and Global Health

    Landscape drives zoonotic malaria prevalence in non-human primates

    Emilia Johnson, Reuben Sunil Kumar Sharma ... Kimberly Fornace

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