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Episode 103: May 2026

In this episode, we hear about the potential of synthetic gene circuits to target cancer, a zebrafish model of cerebral small vessel disease, evidence that psilocybin may alleviate depression, a new technique to make flu vaccines more effective, and why crabs walk sideways.
Episode 103: May 2026

Chapters

  1. 0:37
    Genetic sensors that detect cancer
    Synthetic gene circuits could be used to kill cells in RAS-driven cancers.
    This chapter is based on the following content
  2. 7:28
    What fish can reveal about brain blood vessels
    A gene called foxf2 is linked to blood-vessel damage in the brains of zebrafish starting at an early age.
    This chapter is based on the following content
  3. 16:01
    How hallucinogens work to break the depression deadlock
    Drugs like psilocybin loosen the connections that would otherwise lock in the depression
    This chapter is based on the following content
    • Research Article by Malin Schmidt, Anne Hoffrichter ... Philipp Koch
    • Insight by Jessica L Maltman, Javier González-Maeso
  4. 23:24
    Finding immunological loopholes to block flu
    High-throughput neutralisation tests could lead to a better understanding of the evolution of human influenza.
    This chapter is based on the following content
  5. 31:13
    When did crabs start walking sideways?
    The ability of crabs to walk sideways can be traced back to a single evolutionary origin from a forward-moving ancestor.