Browse our Reviewed Preprints

1. 1. Biochemistry and Chemical Biology

   Metabolic compensation via gluconeogenesis explains the non-essentiality of glycogen phosphorylase as an insecticidal target in Plutella xylostella

   Yifei Zhou, Yanqi Kang ... Jiyuan Liu
2. 1. Structural Biology and Molecular Biophysics

   Improved cryo-EM reconstruction of sub-50 kDa complexes using 2D template matching

   Kexin Zhang, Timothy Grant, Nikolaus Grigorieff
3. 1. Neuroscience

   Foveated metamers of the early visual system

   William F Broderick, Gizem Rufo ... Eero P Simoncelli
4. 1. Cell Biology

   N6-Adenosine Methylation of a Single Site in SARS-CoV-2 5′-UTR Promotes Translation

   Ammar Aly, Gary Scott ... A Pejmun Haghighi
5. 1. Chromosomes and Gene Expression
   2. Physics of Living Systems

   Preferential formation of NUP98-KDM5A condensates at specific H3K4me3-rich loci drives leukemogenic gene expression

   Augusto Berrocal, Jonathan E Sandoval ... Bo Huang
6. 1. Structural Biology and Molecular Biophysics

   Optimising the tilt-increment for in situ cryo-electron tomography

   Maarten W Tuijtel, Tomáš Majtner ... Martin Beck
7. 1. Cancer Biology

   CDK4 or CDK6 upregulation induces DNA replication stress and genomic instability to cause EGFR targeted therapy resistance in lung cancer

   Beatrice Gini, Philippe Gui ... Collin M Blakely
8. 1. Biochemistry and Chemical Biology

   The structure-interaction model of polymyxin lipopeptides with human oligopeptide transporter 2

   Xukai Jiang, Yining Luo ... Jian Li
9. 1. Genetics and Genomics
   2. Evolutionary Biology

   Pre-Cambrian origin of envelope-carrying retrotransposons in metazoans

   Shashank Chary, Rippei Hayashi
10. 1. Biochemistry and Chemical Biology

    A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins

    Daniel J Kelpsch, Liyun Zhang ... Steven A Farber