Thousands of "noncoding" RNAs, 5' "untranslated" regions, and pseudogenes in humans are actually translated, and some of these are likely to express functional proteins.

Lumen extension in intracellular tubes relies on a molecular pathway involving Rho GTPase signaling, cell polarity, and vesicle-tethering proteins.

Natural variations in touch-dependent dopamine signaling tune the perception of spatial patterns in C. elegans.

The RNA-binding protein PTBP1 is recruited to sites near stop codons in retroviral and human mRNAs, shielding them from detection and degradation by the nonsense-mediated mRNA decay pathway.

In invertebrate and vertebrate models of Spinal Muscular Atrophy, diminished SMN protein causes Gemin3-dependent decreases in microRNA function, leading to upregulated M2 muscarinic receptor and deleterious consequences.

RIM binding UNC-13L C2A domain releases UNC-13L from an autoinhibitory homodimeric complex to become fusion-competent, and regulates probability of synaptic vesicle release in the post-priming process.

PLK-1/2-mediated SYP-4 phosphorylation is dependent on crossover precursor formation, triggering a switch in the dynamic state of the synaptonemal complex that reduces the formation of further double-strand breaks at late meiotic prophase.

A genetic screen and live cell imaging show that a newly identified coiled-coil protein called SAS-7 is the earliest acting factor in centriole assembly yet identified in the roundworm Caenorhabditis elegans.

Coordination between crossover designation and synaptonemal complex disassembly is executed via a conserved MAP kinase pathway and is critical for accurate chromosome segregation during meiosis.

Endocytosis is triggered by membrane-associated proteins that transform the clathrin adaptor into an active complex.