9 results found
    1. Developmental Biology

    Specialized impulse conduction pathway in the alligator heart

    Bjarke Jensen, Bastiaan J Boukens ... Vincent M Christoffels
    A specialized conduction pathway for the electrical impulse in the heart, previously thought to be associated with the endothermic mammals and birds only, is also present in the ectothermic crocodiles.
    1. Developmental Biology
    2. Evolutionary Biology

    The alternative regenerative strategy of bearded dragon unveils the key processes underlying vertebrate tooth renewal

    Lotta Salomies, Julia Eymann ... Nicolas Di-Poï
    Analysis of bearded dragon model reveals a novel tooth replacement strategy that demonstrates the critical importance of epithelial patterning, cell migration, and putative stem cell functional specialization in tissue regeneration.
    1. Developmental Biology

    Evolution: The beat goes on

    Tobias Wang
    Why is the alligator heart so similar to the hearts of birds and mammals?
    Version of Record
    Insight
    1. Evolutionary Biology

    Novel neuroanatomical integration and scaling define avian brain shape evolution and development

    Akinobu Watanabe, Amy M Balanoff ... Mark A Norell
    More integrated brains in crown birds evolved through a mosaic assembly of new evolutionary and developmental dynamics across neuroanatomical regions that occurred along the dinosaur-bird transition.
    1. Cell Biology
    2. Evolutionary Biology

    TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants

    Michael Sulak, Lindsey Fong ... Vincent J Lynch
    Elephants escaped enhanced cancer susceptibility by evolving more master tumor suppressor genes.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Caspase-1 activates gasdermin A in non-mammals

    Zachary Paul Billman, Stephen Bela Kovacs ... Edward A Miao
    Amphibians, reptiles, and birds engage pyroptosis using caspase-1 and GSDMA, filling an evolutionary gap in which caspase-1 cleaves GSDME in fish and GSDMD in mammals.
    1. Genetics and Genomics

    Post-meiotic mechanism of facultative parthenogenesis in gonochoristic whiptail lizard species

    David V Ho, Duncan Tormey ... Peter Baumann
    Facultative parthenogenesis in whiptail lizards produces genome-wide homozygosity in offspring.
    1. Cell Biology

    Peroxisomal lactate dehydrogenase is generated by translational readthrough in mammals

    Fabian Schueren, Thomas Lingner ... Sven Thoms
    Whole-genome in silico screening for stop codon contexts that produce elevated translational readthrough and peroxisome targeting reveals that in mammals, the amount of lactate dehydrogenase in the peroxisome is controlled by translational readthrough.
    1. Evolutionary Biology

    Computed tomographic analysis of the dental system of three Jurassic ceratopsians and implications for the evolution of tooth replacement pattern and diet in early-diverging ceratopsians

    Jinfeng Hu, Catherine A Forster ... Fenglu Han
    The tooth replacement pattern of early-diverging ceratopsians helps to understand the origin of the specialized dental system of ceratopsids and provides new insights to feeding strategy transition.

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