Single-cell sequencing of the alveolar bone marrow of apical periodontitis reveals the cellular and molecular composition of the microenvironment and highlights an osteogenic potential within mesenchymal stem cells of inflammatory-related bone diseases.

Cell cycle asynchrony regulates apical cell shape to drive cell division orientation in the apical plane.

High-resolution live and fixed tissue imaging combined with cell and tissue scale data analyses revealed that a ratchet-like constriction of the apical surfaces of cells drives the first step of an epithelial-to-mesenchymal transition taking place during mouse gastrulation.

The composition of inhibitory and excitatory synaptic inputs to the apical dendrites of pyramidal cells in mouse cortex is specific to the type of pyramidal cells.

Incomplete delamination serves as a cellular platform for coordinated tissue movements during development, guiding newly formed progenitor cell groups to the differentiation site.

Apical and basal dendrites contribute differently to single-neuron orientation selectivity, highlighting the impact of feedforward and feedback signal interactions.

Applying a CRISPR knockout screen in polarized intestinal epithelial cells and subsequent phenotypic analyses identified various genes, of which several were previously not associated with epithelial homeostasis, to be relevant for proper epithelial polarization, apical cargo transport, and endo/lysosomal morphology.

In epithelial cells, anillin organizes the medial-apical actomyosin cortex into a contractile load-bearing structure and increases tissue-level stiffness.

Meru is a factor that provides tissue-specific information to the core polarity machinery by linking planar to apical-basal polarity in asymmetrically dividing sensory organ precursors.

Transgenic analysis reveals a role for LEAFY in ferns that supports a trajectory from general to floral meristem-specific function as land plants evolved.