Habituation to mechanical vibration of crawling Drosophila larvae exhibits distinct time constants that characterize desensitization, re-sensitization, and further adaptation to repeated stimulus patterns.

Drosophila larvae manipulated by an automated system can be observed for 30+ hr, and new analysis methods of long-timescale trajectories reveal behavioral features previously inaccessible, such as a bimodal distribution of thermal navigation efficiency in individual animals.

An integrative model of coordinated crawling in fruit fly maggots links neuromuscular dynamics to body-substrate mechanics in the presence of proprioceptive feedback.

A brain descending interneuron can coordinate a switch between two antagonistic behaviors (forward and backward locomotions).

Drosophila larvae foraging adapt to different food quality and distributions modulating specific motor programs, as revealed by behavioral and modeling experiments.

For the first time, action potentials and subthreshold postsynaptic potentials of almost all individual identifiable neurons within a functional unit of the leech nervous system were simultaneously imaged during sensory processing and behavioral generation.

Voltage-dye imaging followed by serial blockface electron microscopy of the same ganglion reveals structure–function relationships of leech motor behaviors.

GABAergic interneurons coordinate synchronous muscle contractions along the length of the fruit fly larva to control the duration between peristaltic waves and locomotion speed.

Connectomic, optogenetic, and high-throughput behavioral analyses identify a descending neuron in the fruit fly larval brain that modifies the timing of nociception-induced rolling.

Reactive oxygen species, previously considered damaging agents linked to pathology, are required for normal neuronal plasticity, including adjustment of synaptic terminal size, maintenance of synaptic physiology and adaptive behavioural responses.