1,568 results found
    1. Neuroscience

    Non-uniform distribution of dendritic nonlinearities differentially engages thalamostriatal and corticostriatal inputs onto cholinergic interneurons

    Osnat Oz, Lior Matityahu ... Joshua A Goldberg
    The membrane nonlinearities of the dendritic arbor of striatal cholinergic interneurons conspire with the spatial distribution of its excitatory inputs to preferentially boost thalamic inputs.
    1. Cell Biology
    2. Neuroscience

    RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation

    Kei Nakayama, Rie Ohashi ... Nobuyuki Shiina
    The formation of long-term memory in mice requires an element of RNA granules that localizes messenger RNAs to dendrites.
    1. Cell Biology
    2. Neuroscience

    Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory

    Yang Niu, Zhonghua Dai ... Jia-Jia Liu
    SNX6 regulates the distribution of a protein called Homer1b/c to distal dendrites, enabling the latter to stabilize the synapses and thereby support memory formation.
    1. Neuroscience

    Revealing the distribution of transmembrane currents along the dendritic tree of a neuron from extracellular recordings

    Dorottya Cserpán, Domokos Meszéna ... Daniel K Wójcik
    A computational method reveals current sources along the dendritic tree of a single neuron of known morphology from extracellular potential.
    1. Cell Biology
    2. Immunology and Inflammation

    Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node

    Shannon M Walsh, Ryan M Sheridan ... Beth Ann Jiron Tamburini
    Antigen-phosphorothioate DNA conjugation provides a vaccination strategy where stable barcodes facilitate the detection and quantification of antigen using single-cell RNA sequencing.
    1. Computational and Systems Biology
    2. Neuroscience

    Dendritic trafficking faces physiologically critical speed-precision tradeoffs

    Alex H Williams, Cian O'Donnell ... Timothy O'Leary
    A simple model of active transport in neurons allows intracellular cargo to find sites of demand using only local signals, but predicts long delays in distributing cargo throughout a dendritic tree.
    1. Genetics and Genomics
    2. Neuroscience

    Characterizing the Spatial Distribution of Dendritic RNA at Single Molecule Resolution

    Jihoon Kim, Jean G Rosario ... Junhyong Kim
    Not revised
    Reviewed Preprint v1
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    • Incomplete
    1. Neuroscience

    Computational models of O-LM cells are recruited by low or high theta frequency inputs depending on h-channel distributions

    Vladislav Sekulić, Frances K Skinner
    The contribution of biophysical ion channels to neuron function can be predicted by taking advantage of an ongoing dialogue between model and experiment.
    1. Neuroscience

    Developmental emergence of two-stage nonlinear synaptic integration in cerebellar interneurons

    Celia Biane, Florian Rückerl ... Laurence Cathala
    Patch-clamp electrophysiology, fluorescence imaging, and computational modeling were used to identify cellular mechanisms underlying maturation of dendritic computations in interneurons.
    1. Neuroscience

    Modeling apical and basal tree contribution to orientation selectivity in a mouse primary visual cortex layer 2/3 pyramidal cell

    Konstantinos-Evangelos Petousakis, Jiyoung Park ... Panayiota Poirazi
    Apical and basal dendrites contribute differently to single-neuron orientation selectivity, highlighting the impact of feedforward and feedback signal interactions.

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