Prostaglandin synthesis and PGE2 receptor activity are essential for mediating segmentation of renal progenitors during pronephros formation in the zebrafish.

Oligodendrocyte-lineage cells secrete L-type prostaglandin synthase in an autocrine loop to promote oligodendrocyte development and myelination.

Prostaglandin E2 inhibits Kv2.2 channels via the EP2/4-PKA signaling pathway, leading to decreased glucose-stimulated action potential firing and insulin secretion in normal pancreatic β-cells.

Astrocytes modulate neuronal networks during hypercapnia, introducing a novel gliotransmitter pathway where prostaglandin E2 regulates breathing.

Prostaglandin E₂-mediated radial spread of PKA activation, caused by calcium transients, is a novel mode of intercellular communication in living mice.

A phosphorylation of receptor interacting RIPK3 switches its pro-necroptosis function to apoptosis that promotes luteal regression which induced by Prostaglandin F2alpha.

In vivo modulation of the prostaglandin, interferon, or granulocyte colony-stimulating factor pathway induces rapid and specific transcriptional changes in hematopoietic stem cells with significant heterogeneity in the cellular response.

Connexin 43 hemichannel activation associated with prostaglandin release in osteocytes plays an important role in anabolic function of mechanical loading on bone tissue and hemichannels could be a potential new therapeutic target for treating bone loss and osteoporosis.

Novel brainstem organotypic cultures that generate rhythmic respiratory motor activity reveal the neural networks that control breathing and a new pathway in the hypercapnic response.