81 results found
    1. Neuroscience

    Functional gradients in the human lateral prefrontal cortex revealed by a comprehensive coordinate-based meta-analysis

    Majd Abdallah, Gaston E Zanitti ... Demian Wassermann
    A comprehensive meta-analysis of the neuroimaging literature reveals that the lateral prefrontal cortex of humans is mainly organized along its rostrocaudal axis according to a unimodal-to-transmodal pattern of network connectivity and a concrete-to-abstract axis of functional associations.
    1. Neuroscience

    Age-related differences in the functional topography of the locus coeruleus and their implications for cognitive and affective functions

    Dániel Veréb, Mite Mijalkov ... Joana B Pereira
    A gradient-based approach is employed to characterize the organization of functional connectivity in the human locus coeruleus, revealing age-related differences and associations with cognitive and affective functions independently from age.
    1. Computational and Systems Biology
    2. Developmental Biology

    Modelling the emergence of whisker barrels

    Sebastian S James, Leah A Krubitzer, Stuart P Wilson
    Whisker barrels provide clues about neocortical development, as computer modelling shows that barrels can self-organize, based on competition between adjacent thalamocortical axons, suggesting that genetic instruction plays a secondary role.
    1. Cell Biology
    2. Neuroscience

    Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance

    Kentarou Baba, Wataru Yoshida ... Naoyuki Inagaki
    Shootin1a, through its spatially regulated phosphorylation within growth cones, mediates the gradient reading and mechanoresponse for netrin-1-induced axon guidance.
    1. Computational and Systems Biology
    2. Neuroscience

    Neuronal timescales are functionally dynamic and shaped by cortical microarchitecture

    Richard Gao, Ruud L van den Brink ... Bradley Voytek
    Invasive electrophysiological recording measures neuronal transmembrane current timescales across human cortex, which lengthens from sensory to association regions, follows variations in ion channel expressions, and alters with behavior and aging.
    1. Neuroscience

    Postnatal development of retrosplenial projections to the parahippocampal region of the rat

    Jørgen Sugar, Menno P Witter
    Retrosplenial axons arriving in the parahippocampal region around the first day after birth are topographically organized, similarly to what has been reported in the adult.
    1. Developmental Biology

    Position-dependent plasticity of distinct progenitor types in the primitive streak

    Filip J Wymeersch, Yali Huang ... Valerie Wilson
    Neuromesodermal and lateral/ventral mesoderm progenitors represent distinct committed states, governed by separate regulatory logics.
    1. Developmental Biology
    2. Neuroscience

    A mutant with bilateral whisker to barrel inputs unveils somatosensory mapping rules in the cerebral cortex

    Nicolas Renier, Chloé Dominici ... Alain Chédotal
    The somatosensory cortex doesn't integrate mixed bilateral inputs, as partially uncrossing projections from the whiskers duplicates their representation by segregating lateralized inputs from each side of the head.
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Neuroanatomical abnormalities in a nonhuman primate model of congenital Zika virus infection

    Danielle Beckman, Adele MH Seelke ... Eliza Bliss-Moreau
    Fetal Zika virus’ direct infection of the brain causes neuroanatomical pathology that tracks with the brain development, following a caudal-to-rostral trajectory, even in individuals who do not develop microcephaly.
    1. Physics of Living Systems

    The Reissner fiber under tension in vivo shows dynamic interaction with ciliated cells contacting the cerebrospinal fluid

    Celine Bellegarda, Guillaume Zavard ... Claire Wyart
    Experimental manipulations and a mechanical model of the fiber reveal that the Reissner fiber is under heterogenous tension in vivo, and interacts with the motile cilia of diverse cells contacting the cerebrospinal fluid.

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