2,218 results found
    1. Neuroscience

    Fast-spiking GABA circuit dynamics in the auditory cortex predict recovery of sensory processing following peripheral nerve damage

    Jennifer Resnik, Daniel B Polley
    Dynamic regulation of feedforward inhibition from parvalbumin-expressing inhibitory neurons is linked to the gradual restoration of cortical sensory processing following auditory nerve damage.
    1. Immunology and Inflammation

    Neuron-associated macrophage proliferation in the sensory ganglia is associated with peripheral nerve injury-induced neuropathic pain involving CX3CR1 signaling

    Rafaela M Guimarães, Conceição E Aníbal-Silva ... Thiago M Cunha
    CX3CR1-signaling in sensory ganglia macrophages mediates their proliferation/activation, as well as the production of pro-inflammatory mediators that contribute to neuropathic pain.
    1. Developmental Biology
    2. Neuroscience

    Ordered arrangement of dendrites within a C. elegans sensory nerve bundle

    Zhiqi Candice Yip, Maxwell G Heiman
    A nerve bundle is not simply a cable of wires, but has order within it.
    1. Neuroscience

    The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles

    Lishi Li, David D Ginty
    Close examination of lanceolate mechanosensory complexes has revealed clues about the ways that sensory nerves detect the movement of hairs and shown than terminal Schwann cells are needed to maintain and regenerate these intricate structures.
    1. Neuroscience

    Interaction of human keratinocytes and nerve fiber terminals at the neuro-cutaneous unit

    Christoph Erbacher, Sebastian Britz ... Nurcan Üçeyler
    Sensory nerve fiber ending ensheathment and connexin 43 contacts by keratinocytes at the neuro-cutaneous unit can be visualized and quantified at super-resolution in human skin.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Complement and CD4+ T cells drive context-specific corneal sensory neuropathy

    Derek J Royer, Jose Echegaray-Mendez ... Daniel JJ Carr
    The complement pathway can contribute to corneal sensation loss and nerve damage during ocular surface inflammation.
    1. Neuroscience

    Calretinin positive neurons form an excitatory amplifier network in the spinal cord dorsal horn

    Kelly M Smith, Tyler J Browne ... Brett A Graham
    A signal amplifier network that transmits mechanical pain is delineated through characterising an excitatory interneuron population in the spinal cord dorsal horn and defining the postsynaptic populations they regulate.
    1. Medicine

    Senescence of endplate osteoclasts induces sensory innervation and spinal pain

    Dayu Pan, Kheiria Gamal Benkato ... Xu Cao
    Depleting senescent osteoclasts using the senolytic drug Navitoclax (ABT263) can reduce sensory innervation in the endplate and attenuate low back pain, thus representing a potent therapy for treating spinal pain.
    1. Neuroscience

    Anatomical basis and physiological role of cerebrospinal fluid transport through the murine cribriform plate

    Jordan N Norwood, Qingguang Zhang ... Patrick J Drew
    Chemical ablation of olfactory sensory neurons blocks cerebrospinal fluid outflow into the nasal epithelium, leading to alterations of cerebrospinal fluid dynamics.
    1. Developmental Biology

    Taste bud formation depends on taste nerves

    Di Fan, Zoubida Chettouh ... Jean-François Brunet
    The sensory nerves that carry sensations from the taste buds to the brain induce the formation of the taste buds in the embryo.

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