772 results found
    1. Developmental Biology

    Ancient origin of lubricated joints in bony vertebrates

    Amjad Askary, Joanna Smeeton ... J Gage Crump
    Zebrafish have lubricated joints similar to ours and are a tractable model for arthritis research.
    1. Cell Biology
    2. Evolutionary Biology

    Lipid droplet biology and evolution illuminated by the characterization of a novel perilipin in teleost fish

    James G Granneman, Vickie A Kimler ... Ryan Thummel
    Phylogenetic, biochemical, and genetic techniques reveal a novel and ancient member of the Perilipin family, termed Plin6, that functions to concentrate and traffic lipophilic skin pigment in teleost fish.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The impact of local genomic properties on the evolutionary fate of genes

    Yuichiro Hara, Shigehiro Kuraku
    The genomic features associated with a gene fate to loss have been retained for approximately 500 million years during evolution, and the genes with these features exhibit restricted expression profiles, leading to the genes being less important.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates

    Wenjie Xu, Chenglong Zhu ... Kun Wang
    The hadal snailfish rapidly evolved and adapted to extreme deep-sea environments, modifying crucial genes and enhancing tolerance to high-hydrostatic pressure through ferritin gene duplication.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Gap junctions composed of connexins 41.8 and 39.4 are essential for colour pattern formation in zebrafish

    Uwe Irion, Hans Georg Frohnhöfer ... Christiane Nüsslein-Volhard
    Melanophores and xanthophores interact via heteromeric gap junctions composed of Connexin 41.8 and Connexin 39.4 to establish the adult pigment pattern in zebrafish.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The whale shark genome reveals patterns of vertebrate gene family evolution

    Milton Tan, Anthony K Redmond ... Timothy Read
    The new whale shark genome assembly represents the best gapless chondrichthyan genome assembly yet, and comparative genomic analyses provide insights into the evolution of vertebrate genome origins, immunity, and gigantism.
    1. Cell Biology
    2. Developmental Biology

    Tight Junction Protein 1a regulates pigment cell organisation during zebrafish colour patterning

    Andrey Fadeev, Jana Krauss ... Christiane Nüsslein-Volhard
    The changes in shape of iridophores that underlie adult colour pattern formation in zebrafish depend on the levels of Tight Junction Protein 1a in these cells.
    1. Developmental Biology
    2. Evolutionary Biology

    A novel cis-regulatory element drives early expression of Nkx3.2 in the gnathostome primary jaw joint

    Jake Leyhr, Laura Waldmann ... Tatjana Haitina
    Jaw joint regulatory sequence 1 (JRS1) is deeply conserved in most jawed vertebrates and displays a specific enhancer activity in the developing primary jaw joint that contributes to early nkx3.2 gene expression and jaw joint morphology.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Transcriptional rewiring over evolutionary timescales changes quantitative and qualitative properties of gene expression

    Chiraj K Dalal, Ignacio A Zuleta ... Alexander D Johnson
    Rewiring of transcriptional circuits can preserve a basic output yet alter almost all of the circuit's quantitative and qualitative features.
    1. Ecology

    First bone-cracking dog coprolites provide new insight into bone consumption in Borophagus and their unique ecological niche

    Xiaoming Wang, Stuart C White ... Z Jack Tseng
    Fossilized feces (coprolites) of extinct bone-crushing dogs, Borophagus parvus, from late Miocene (6 million years ago) of California demonstrates consumption and preservation of bones in digestive tracts and potential social hunting behavior by these predators.

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