Browse our latest Biochemistry and Chemical Biology articles

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    1. Biochemistry and Chemical Biology

    Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy

    Boglarka Zambo, Evelina Edelweiss ... Gergo Gogl
    1. Biochemistry and Chemical Biology

    Kinases in motion: impact of protein and small molecule interactions on kinase conformations

    Valentina Kugler, Selina Schwaighofer ... Eduard Stefan
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    β-catenin inhibition disrupts the homeostasis of osteogenic/adipogenic differentiation leading to the development of glucocorticoid-induced osteonecrosis of the femoral head

    Chenjie Xia, Huihui Xu ... Hongting Jin
    Deletion of β-catenin in Col2+ progenitor cells shifts their commitment from osteoblasts to adipocytes, leading to a full spectrum of disease phenotype of glucocorticoid-induced osteonecrosis of the femoral head in adult mice.
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    A translation proofreader of archaeal origin imparts multi-aldehyde stress tolerance to land plants

    Pradeep Kumar, Ankit Roy ... Rajan Sankaranarayanan
    Genetic, biochemical, and bioinformatic analyses reveal how expanding metabolic repertoire interferes with fundamental processes like protein synthesis inside cells and the role of D-aminoacyl-tRNA deacylase2 in protecting these processes during terrestrialisation.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Mapping the architecture of the initiating phosphoglycosyl transferase from S. enterica O-antigen biosynthesis in a liponanoparticle

    Greg J Dodge, Alyssa J Anderson ... Barbara Imperiali
    Structural, functional, and bioinformatics analyses further understanding of the initial steps of prokaryotic glycoconjugate biosynthesis catalyzed by the large class of membrane-embedded monotopic phosphoglycosyl transferase superfamily.
    1. Biochemistry and Chemical Biology

    Rapid, DNA-induced interface swapping by DNA gyrase

    Thomas Germe, Natassja G. Bush ... Anthony Maxwell