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Page 6 of 89
Computational and Systems Biology
Cancer Biology
Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures
Daniel Osorio, Parastoo Shahrouzi ... Marieke L Kuijjer
Cancer Biology
Genetics and Genomics
Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer
Arkajyoti Bhattacharya, Thijs S Stutvoet ... Rudolf SN Fehrmann
Independent component analysis of ovarian cancer transcriptomes reveals distinct transcriptional patterns associated with overall survival.
Cancer Biology
Causal associations between plasma proteins and prostate cancer: a Proteome-Wide Mendelian Randomization
Chen Lin, Rong Zhuona ... Pang Xiaocong
Cell Biology
Cancer Biology
Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics
David Papadopoli, Ranveer Palia ... Ivan Topisirovic
Cancer Biology
Developmental Biology
VGLL2 and TEAD1 fusion proteins identified in human sarcoma drive YAP/TAZ-independent tumorigenesis by engaging EP300
Susu Guo, Xiaodi Hu ... Junhao Mao
Characterization of recurrent fusion proteins in rhabdomyosarcoma identified a Hippo pathway-independent mechanism involving VGLL2 and TEAD1 driving oncogenic transformation.
Cancer Biology
Repression of the Wnt pathway effector TCF7L2 reverses lethal cachexia in mice with intestinal cancers
Mei Ling Leong, Christiane Ruedl, Klaus Karjalainen
Cancer Biology
The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells
Jie Fang, Shivendra Singh ... Jun Yang
Drastic differences in genetic and epigenetic fitness of MYC-driven cancer cells in 3D vs 2D culture.
Cell Biology
Cancer Biology
Human
RAP2A
Homolog of the
Drosophila
Asymmetric Cell Division Regulator
Rap2l
Targets the Stemness of Glioblastoma Stem Cells
Maribel Franco, Ricardo Gargini ... Ana Carmena
Cancer Biology
Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
Shan Li, Kai Song ... John K Lee
Cell Biology
Cancer Biology
Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling
Rachel Nakagawa, Andrew Beardsley ... Andrei Goga
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