iCAF-mediated immune escape and promoted tumor angiogenesis via VEGFA/B-VEGFR1 pathway indicate that a combination of immunotherapies and anti-angiogenic targeted therapy may be effective for H. pylori infection-associated gastric cancer.
Integrated single-cell RNA-seq analysis identifies ferroptosis-driven tumor microenvironment features, enabling a prognostic risk model and therapeutic targets to advance precision medicine for triple-negative breast cancer.
The development of an automated micronucleus segmentation program enables population-level comparisons between cells with and without micronuclei and defines a highly limited response to micronucleus formation or rupture.
Inhibiting the p38 MAPK-MK2 signaling pathway significantly boosts the efficacy of microtubule-targeting agents specifically in breast cancer cells, highlighting a potential new therapeutic strategy for improved cancer treatment.
