Saima Usman, William Andrew Yeudall ... Ahmad Waseem
Disruption of vimentin–actin interaction induces XIST expression and drives epithelial-to-mesenchymal transition and stem cell-like traits in breast cancer cells, enhancing oncogenic behaviour in nude mice independent of oestrogen.
The N-terminally truncated Δ133p53α and Δ160p53α isoforms exert dominant-negative effects through co-aggregation with p53, disrupting its transcriptional activity and cellular distribution, thereby contributing to cancer development.
Patients with microsatellite stable/low microsatellite instability mismatch repair-proficient metastatic colorectal cancer may be sensitive to tislelizumab treatment after receiving Gamma Knife stereotactic radiotherapy.
A machine learning-derived multi-gene score effectively predicts radiation sensitivity in nasopharyngeal carcinoma by integrating immune characteristics and radiosensitivity-related pathways.
iCAF-mediated immune escape and promoted tumor angiogenesis via VEGFA/B-VEGFR1 pathway indicate that a combination of immunotherapies and anti-angiogenic targeted therapy may be effective for H. pylori infection-associated gastric cancer.
