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Ferroptosis is an evolutionary ancient process that is counterbalanced by distant peroxidases, GPx4 in mammals and tryparedoxin peroxidases in trypanosomes, and can be induced at distinct subcellular membranes depending on the individual cell type.

Planar cell polarity proteins display dynamic spatial and temporal patterns of enrichment that tightly correlate with myosin-dependent cell behaviors during neural tube closure.

Cryo-electron tomography of mammalian and fly centrioles shows that the ninefold symmetry of centrioles is set by species-specific microtubule linkers.

The hair follicle dermal condensate is populated via migration, and the cells exhibit early changes in cell shape and cell cycle status; Fgf20 primes these cellular and molecular events.

Emergence of hematopoietic stem cells from an aortic component is a unique phenomenon of cell extrusion, with no equivalent in cell biology, and which is adapted to environmental constraints exerted by endothelial cells and hemodynamics forces.

Splicing by QKI and RBFOX1 regulates the function of the actin-binding protein FLNB by creating an isoform frequently observed in human cancers that dictates tumor cell plasticity.

Comprehensive investigation reveals the variability and importance of the nuclear pore complex in HIV-1 infection and the activity of the antiretroviral protein, MX2.

Embryonic development requires autophagy-dependent degradation of ribosomal RNAs.

Engagement of both host and parasite signaling pathways proves a novel approach for developing improved anti-parasitic therapies.

Integrin and actin associated proteins are resolved into four layers within myofibril attachments, an architecture requiring balanced positive and negative regulation of integrin adhesion with integrated mechanotransduction and actin pathways.