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The scaffold protein SAV1 counteracts PP2A to activate Hippo kinases.

A protein interaction screen revealed desmosomes as a scaffold for the COP9 de-neddylating complex, to promote epidermal differentiation by governing the balance of Nedd8 and Ubiquitin modifications on Epidermal Growth Factor Receptor.

COPI vesicle coat protein recognizes a ubiquitin sorting signal on an exocytic v-SNARE to mediate recycling.

Three-dimensional fluorescence imaging of microbial eukaryotes in environmental samples allows accurate automated taxonomic profiling and quantitative data about ultrastructures and interactions of organisms.

During intraflagellar transport (IFT), kinesin-II dissociates from IFT trains at the flagellar tip and its diffusion in flagella serves as a negative feedback mechanism that facilitates flagellar length control in Chlamydomonas.

A new imaging technique sheds light on how cilia regulate their length and growth.

Uncoupling of dynamin polymerization and GTPase activity can be induced with dynamin, which allows in vivo visualization of its activity at endocytic pits.

The E3 ubiquitin ligase RNF145 is shown to contribute to crosstalk between the LXR and SREBP-2 pathways in the regulation of cholesterol homeostasis.

Loading of CD95 and CD95L-derived sequences into the RNA-induced silencing complex elicits a distinct form of RNAi-mediated cell death of cancer cells that results from the targeting of multiple survival genes.

Deletion of delta-tubulin or epsilon-tubulin in human cells results in loss of centriolar triplet microtubules and defects in centriole structure and inheritance.