Browse our latest Cell Biology articles

Page 99 of 318
    1. Cell Biology
    2. Physics of Living Systems

    Cortical waves mediate the cellular response to electric fields

    Qixin Yang, Yuchuan Miao ... Wolfgang Losert
    Electrical and biomechanical stimuli directly bias cortical signal transduction and cytoskeletal waves, and the direct bias induced by an electric field develops slowly compared to the rapid surface-receptor-mediated response to chemotactic gradients.
    1. Cell Biology
    2. Medicine

    Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels

    Chiara Piantoni, Manuel Paina ... Mirko Baruscotti
    A Traditional Chinese Medicine botanical drug exerts a competitive antagonism on the cAMP-induced modulation of sinoatrial node pacemaker channels and this functional inhibition reduces the slope of the diastolic depolarization hence spontaneous cell automaticity.
    1. Cell Biology

    A light-gated transcriptional recorder for detecting cell-cell contacts

    Kelvin F Cho, Shawn M Gillespie ... Alice Y Ting
    TRACC (Transcriptional Readout Activated by Cell-cell Contacts) is an engineered molecular tool that detects and records cell-cell contacts in mammalian systems.
    1. Cell Biology
    2. Developmental Biology

    A neural progenitor mitotic wave is required for asynchronous axon outgrowth and morphology

    Jérôme Lacoste, Hédi Soula ... Sophie Louvet-Vallée
    Timing of neural precursor cells division controls the order of development of sensory neurons, which in turn determines their axon terminal pattern and ultimately fly behaviour.
    1. Cell Biology
    2. Developmental Biology

    Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions

    Giorgio Oliviero, Sergey Kovalchuk ... Ole N Jensen
    Quantitative proteomics reveals the diversity and heterogeneity of nuclear proteomes in mammalian organs and identifies the molecular features of ageing.
    1. Cell Biology
    2. Developmental Biology

    The transcription factor Xrp1 orchestrates both reduced translation and cell competition upon defective ribosome assembly or function

    Marianthi Kiparaki, Chaitali Khan ... Nicholas E Baker
    Ribosomal protein mutations, mutations that affect ribosomal RNA synthesis, or function of the mature ribosome, trigger a transcriptional response mediated by Xrp1 expression which reduces cellular translation via eIF2-alpha phosphorylation and renders cells liable to competition with wild-type neighbors.
    1. Cancer Biology
    2. Cell Biology

    The out-of-field dose in radiation therapy induces delayed tumorigenesis by senescence evasion

    Erwan Goy, Maxime Tomezak ... Corinne Abbadie
    Irradiation of normal human fibroblasts and mice in conditions mimicking standard external X-ray radiotherapy protocols highlights that noncancerous cells surrounding the planning target volume accumulate DNA single-strand breaks but almost no double-strand breaks, putting them in a pre-cancerous senescent state.
    1. Cell Biology

    In vivo transcriptomic profiling using cell encapsulation identifies effector pathways of systemic aging

    Omid Mashinchian, Xiaotong Hong ... C Florian Bentzinger
    Cell encapsulation-based transcriptional profiling using myogenic progenitors reveals that long-range factors in the aged systemic environment induce a wide range of signaling pathways in a niche-independent manner.
    1. Cell Biology

    Tom70-based transcriptional regulation of mitochondrial biogenesis and aging

    Qingqing Liu, Catherine E Chang ... Chuankai Zhou
    Tom70 connects the mitochondrial import to the nuclear transcriptional activity of mitochondrial proteins and controls mitochondrial biogenesis defects during aging.
    1. Cell Biology
    2. Medicine

    SOX4 facilitates PGR protein stability and FOXO1 expression conducive for human endometrial decidualization

    Pinxiu Huang, Wenbo Deng ... Shuangbo Kong
    A biochemical approach shows that SOX4 guaranteed the PGR protein stability through repressing the ubiquitin E3 ligase HERC4, to make the stroma cell conducive for response to progesterone and decidualization.